Self-assembled nanostructures from amphiphilic globular protein–polymer hybrids
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DOI: 10.1007/s00289-017-2176-y
Abstract: Amphiphilic globular protein–polymer hybrids, consisting of poly(methyl methacrylate) (PMMA) as hydrophobic tail and globular protein as hydrophilic head, are prepared by the end-functional PMMA covalently binding to the primary amino groups of bovine serum albumin… read more here.
Keywords: protein; polymer hybrids; protein polymer; self assembled ... See more keywords
Self-Assembled Recombinant Elastin and Globular Protein Vesicles with Tunable Properties for Diverse Applications
Sign Up to like & getrecommendations! Published in 2024 at "Accounts of Chemical Research"
DOI: 10.1021/acs.accounts.3c00694
Abstract: Conspectus Vesicles are self-assembled structures comprised of a membrane-like exterior surrounding a hollow lumen with applications in drug delivery, artificial cells, and micro-bioreactors. Lipid or polymer vesicles are the most common and are made of… read more here.
Keywords: size; protein vesicles; globular protein; protein ... See more keywords
An Atomic and Molecular Insight into How PFOA Reduces α-Helicity, Compromises Substrate Binding, and Creates Binding Pockets in a Model Globular Protein.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.4c02934
Abstract: Per- and polyfluoroalkyl substances (PFAS) pose significant health risks due to their widespread presence in various environmental and biological matrices. However, the molecular-level mechanisms underlying the interactions between PFAS and biological constituents, including proteins, carbohydrates,… read more here.
Keywords: blg; atomic molecular; pfoa; globular protein ... See more keywords
A globular protein exhibits rare phase behavior and forms chemically regulated orthogonal condensates in cells
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DOI: 10.1038/s41467-025-57886-4
Abstract: Proteins with chemically regulatable phase separation are of great interest in the fields of biomolecular condensates and synthetic biology. Intrinsically disordered proteins (IDPs) are the dominating building blocks of biomolecular condensates which often lack orthogonality… read more here.
Keywords: orthogonal condensates; biology; phase behavior; globular protein ... See more keywords
Non-ergodicity of a globular protein extending beyond its functional timescale
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc03069a
Abstract: Internal motions of folded proteins have been assumed to be ergodic, i.e., that the dynamics of a single protein molecule averaged over a very long time resembles that of an ensemble. Here, by performing single-molecule… read more here.
Keywords: globular protein; protein extending; non ergodicity; ergodicity globular ... See more keywords
Thermodynamics of globular protein native structure
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2022.2046637
Abstract: Abstract The temperature dependence of the partial heat capacity of the native protein structure in an aqueous solution has been analyzed. It is shown that the strictly linear temperature dependence is due to the contributions… read more here.
Keywords: globular protein; thermodynamics globular; structure; protein native ... See more keywords