Globularifolin exerts anticancer effects on glioma U87 cells through inhibition of Akt/mTOR and MEK/ERK signaling pathways in vitro and inhibits tumor growth in vivo.
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DOI: 10.1016/j.biochi.2017.09.005
Abstract: Gliomas are the most recurrently occurring primary malignancies in the central nervous system. Despite surgical interventions, chemo- and radiotherapy, the results are unfortunately poor. Therefore, there is pressing need to explore more effective and efficient… read more here.
Keywords: u87 cells; inhibition akt; globularifolin; glioma ... See more keywords