Glomerular disease patients have higher odds not to reach quality targets in chronic dialysis compared with CAKUT patients: analyses from a nationwide German paediatric dialysis registry
Sign Up to like & getrecommendations! Published in 2019 at "Pediatric Nephrology"
DOI: 10.1007/s00467-019-04218-6
Abstract: BackgroundPaediatric dialysis patients still suffer from high morbidity rates. To improve this, quality assurance programs like the German QiNKid (Quality in Nephrology for Children)-Registry have been developed. In our study, the significance of underlying renal… read more here.
Keywords: nephrology; disease patients; disease; glomerular disease ... See more keywords
Basement membrane defects in CD151-associated glomerular disease
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric Nephrology"
DOI: 10.1007/s00467-022-05447-y
Abstract: CD151 is a cell-surface molecule of the tetraspanin family. Its lateral interaction with laminin-binding integrin ɑ3β1 is important for podocyte adhesion to the glomerular basement membrane (GBM). Deletion of Cd151 in mice induces glomerular dysfunction,… read more here.
Keywords: cd151; microscopy; disease; cd151 associated ... See more keywords
Stem cell therapy: An emerging modality in glomerular diseases.
Sign Up to like & getrecommendations! Published in 2017 at "Cytotherapy"
DOI: 10.1016/j.jcyt.2016.11.003
Abstract: The kidney has been considered a highly terminally differentiated organ with low proliferative potential and thus unlikely to undergo regeneration. Glomerular disease progresses to end-stage renal disease (ESRD), which requires dialysis or renal transplantation for… read more here.
Keywords: stem cell; cell; cell therapy; glomerular disease ... See more keywords
Critical evaluation of cancer risks in glomerular disease
Sign Up to like & getrecommendations! Published in 2022 at "Translational Oncology"
DOI: 10.1016/j.tranon.2022.101376
Abstract: Highlights • The increased cancer incidence in patients with glomerular disease can be secondary to an intrinsic immune dysfunction associated with the disease or/and extrinsic factors, especially immunosuppressants.• Paraneoplastic glomerulopathy is sometimes misdiagnosed as primary… read more here.
Keywords: critical evaluation; cancer risks; evaluation cancer; disease ... See more keywords
COVID-19 in patients with glomerular disease.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in nephrology and hypertension"
DOI: 10.1097/mnh.0000000000000769
Abstract: PURPOSE OF REVIEW Managing patients with glomerular disease during the COVID-19 pandemic has been challenging, as the infection risk associated with immunosuppression must be balanced against the need to control severe glomerular disease that can… read more here.
Keywords: risk; vaccination; disease; glomerular disease ... See more keywords
Seven suggestions for successful SGLT2i use in glomerular disease - a standalone CKD therapy?
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Nephrology and Hypertension"
DOI: 10.1097/mnh.0000000000000786
Abstract: Purpose of review Recent advances in the world of glomerular diseases have largely focussed on remission induction with immune modulating therapy. It is well recognised that even with the best available treatments, patients with glomerular… read more here.
Keywords: disease; glomerular disease; nephrology; therapy ... See more keywords
Association between Opisthorchis viverrini Infection and Glomerular Disease in Thailand.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of nephrology"
DOI: 10.1159/000521780
Abstract: INTRODUCTION Opisthorchis viverrini (OV) is a major cause of infection in Southeast Asia. Previous studies in mouse models have shown that OV infection can contribute to immune-complex glomerulonephritis (GN). However, OV infection in human kidney… read more here.
Keywords: infection; glomerular disease; kidney tissue; tissue ... See more keywords
Organoid single cell profiling identifies a transcriptional signature of glomerular disease.
Sign Up to like & getrecommendations! Published in 2019 at "JCI insight"
DOI: 10.1172/jci.insight.122697
Abstract: Podocyte injury is central to many forms of kidney disease, but transcriptional signatures reflecting podocyte injury and compensation mechanisms are challenging to analyze in vivo. Human kidney organoids derived from pluripotent stem cells (PSCs), a… read more here.
Keywords: disease; glomerular disease; signature; organoid single ... See more keywords
Direct Oral Anticoagulants Reduce Hypercoagulopathy and Preserve Podocyte Function in an Experimental Model of Glomerular Disease
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DOI: 10.1182/blood-2020-139889
Abstract: Proteinuric glomerular diseases are a leading cause of chronic kidney disease (CKD). Both pre-CKD glomerular disease and established CKD are major risk factors for thrombosis. Glomerular capillary podocyte injury is a key determinant of CKD… read more here.
Keywords: model glomerular; disease; podocyte; ckd ... See more keywords
Temporal trends in biopsy proven glomerular disease in Uruguay, 1990-2014
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DOI: 10.1371/journal.pone.0206637
Abstract: Our aim is to describe variations in the incidence rates of glomerular disease diagnosed by renal biopsies performed in Uruguay over the last 25 years in relation to sex, age, clinical presentation and histological diagnosis.… read more here.
Keywords: incidence rates; pmp; 1990 2014; glomerular disease ... See more keywords
Basement Membrane Defects in Genetic Kidney Diseases
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2018.00011
Abstract: The glomerular basement membrane (GBM) is a specialized structure with a significant role in maintaining the glomerular filtration barrier. This GBM is formed from the fusion of two basement membranes during development and its function… read more here.
Keywords: gbm; basement membrane; disease; glomerular disease ... See more keywords