Pleiotropic effects of GLP-1RAs on peripheral artery disease: Is there any hope?
Sign Up to like & getrecommendations! Published in 2023 at "Diabetes/metabolism research and reviews"
DOI: 10.1002/dmrr.3627
Abstract: NA This article is protected by copyright. All rights reserved. read more here.
Keywords: effects glp; artery disease; peripheral artery; pleiotropic effects ... See more keywords
GLP-1 receptor agonists and risk of cancer in type 2 diabetes: an updated meta-analysis of randomized controlled trials
Sign Up to like & getrecommendations! Published in 2019 at "Endocrine"
DOI: 10.1007/s12020-019-02055-z
Abstract: Some preliminary studies reported a link between GLP-1 receptor agonists (GLP-1RAs) and thyroid/pancreatic neoplasms, while its human relevance remained undetermined. The present meta-analysis was performed to collect information on cancers associated with GLP-1RAs in patients… read more here.
Keywords: risk; glp 1ras; overall cancer; cancer ... See more keywords
The Role of the Pharmacist in Managing Type 2 Diabetes with Glucagon-Like Peptide-1 Receptor Agonists as Add-On Therapy
Sign Up to like & getrecommendations! Published in 2017 at "Advances in Therapy"
DOI: 10.1007/s12325-017-0491-1
Abstract: AbstractThe prevalence and associated clinical burden of type 2 diabetes (T2D) is increasing in the USA and other countries. As a consequence, the role of the pharmacist in managing T2D is expanding, and it is… read more here.
Keywords: glucagon like; glp 1ras; pharmacist managing; type diabetes ... See more keywords
Regional variation of effects of new antidiabetic medications in cardiovascular outcome trials.
Sign Up to like & getrecommendations! Published in 2021 at "American heart journal"
DOI: 10.1016/j.ahj.2021.06.001
Abstract: BACKGROUND In international trials, glucagon-like protein-1 receptor agonists (GLP-1RAs) and sodium-glucose cotransporter-2 inhibitors (SGLT2Is) were effective in improving cardiovascular (CV) outcomes. METHODS We assessed the effect of GLP-1RAs and SGLT2Is treatment effect on CV endpoints… read more here.
Keywords: glp 1ras; effect; regional variation; variation effects ... See more keywords
Comparative efficacy and safety of 8 GLP-1RAs in patients with type 2 diabetes: a network meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Diabetes research and clinical practice"
DOI: 10.1016/j.diabres.2021.108904
Abstract: AIMS To inform clinical practice by comparing and ranking the lowing blood glucose and weight-loss abilities of 8 glucagon-like peptide-1 receptor agonists (GLP-1RAs) in patients with type 2 diabetes (T2D). METHODS We searched PubMed, EMBASE,… read more here.
Keywords: patients type; glp 1ras; safety; type diabetes ... See more keywords
The effects of glucagon-like peptide-1 receptor agonists on glycemic control and anthropometric profiles among diabetic patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis of randomized controlled trials.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2020.173823
Abstract: This study was undertaken to assess the effects of glucagon-like peptide-1 receptor agonists (GLP-1RAs), mainly liraglutide and exenatide, on glycemic control and anthropometric profiles to see if they are effective in treating patients with non-alcoholic… read more here.
Keywords: glucagon like; glp 1ras; effects glucagon; receptor agonists ... See more keywords
CONTEMPORARY NATIONAL PATTERNS OF ELIGIBILITY AND UTILIZATION OF NOVEL CARDIOPROTECTIVE ANTI-HYPERGLYCEMIC AGENTS IN TYPE 2 DIABETES
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(21)02893-x
Abstract: Background Sodium glucose transporter-2 (SGLT-2) inhibitors and glucagon-like peptide-1 receptor agonists (GLP-1RAs) effectively lowered cardiovascular risk in large clinical trials for patients with type 2 diabetes at high risk for these complications, and have recommended… read more here.
Keywords: inhibitors glp; contemporary national; sglt inhibitors; type diabetes ... See more keywords
Exenatide: pharmacokinetics, clinical use, and future directions
Sign Up to like & getrecommendations! Published in 2017 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2017.1282463
Abstract: ABSTRACT Introduction: The first-in-class glucagon-like peptide-1 receptor agonist (GLP-1RA) exenatide, which was initially approved in 2005, is available in twice-daily (BID) and once-weekly (QW) formulations. Clinical trial data suggest both formulations are effective and safe… read more here.
Keywords: pharmacokinetics clinical; clinical use; glp 1ras; exenatide pharmacokinetics ... See more keywords
Spotlight on Canagliflozin 300: review of its efficacy and an indirect comparison to other SGLT-2 inhibitors and long-acting GLP-1 receptor agonists
Sign Up to like & getrecommendations! Published in 2017 at "Expert Review of Clinical Pharmacology"
DOI: 10.1080/17512433.2017.1318061
Abstract: ABSTRACT Introduction: Both sodium-glucose co-transporter-2 inhibitors (SGLT-2Is) and glucagon-like peptide-1 receptor agonists (GLP-1RAs) have been consistently found to lower blood glucose, body weight and systolic blood pressure (SBP) in patients with type 2 diabetes mellitus… read more here.
Keywords: glp 1ras; sglt 2is; canagliflozin 300; receptor agonists ... See more keywords
META-ANALYSIS ASSESSING THE IMPACT OF PRIOR HEART FAILURE AND CHRONIC KIDNEY DISEASE ON THE CARDIOVASCULAR EFFICACY OF GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONISTS.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of hypertension"
DOI: 10.1097/01.hjh.0000837320.01511.6f
Abstract: OBJECTIVE Chronic kidney disease (CKD) and heart failure (HF) represent common co-morbidities in patients with type 2 diabetes mellitus (T2DM), constituting an additional burden that boosts overall morbidity and mortality. Therefore, we sought to determine… read more here.
Keywords: heart failure; chronic kidney; efficacy; kidney disease ... See more keywords
Long-acting GLP-1RAs: An overview of efficacy, safety, and their role in type 2 diabetes management.
Sign Up to like & getrecommendations! Published in 2020 at "JAAPA : official journal of the American Academy of Physician Assistants"
DOI: 10.1097/01.jaa.0000669456.13763.bd
Abstract: Over recent decades, an improved understanding of the pathophysiology of type 2 diabetes mellitus (T2DM) and glucose regulation has led to innovative research and new treatment paradigms. The discovery of the gut peptide glucagon-like peptide-1… read more here.
Keywords: glp; acting glp; type diabetes; long acting ... See more keywords