GLP-1/GIP analogs: potential impact in the landscape of obesity pharmacotherapy
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DOI: 10.1080/14656566.2023.2192865
Abstract: ABSTRACT Introduction Obesity is recognized as a major healthcare challenge. Following years of slow progress in discovery of safe, effective therapies for weight management, recent approval of the glucagon-like peptide 1 receptor (GLP-1R) mimetics, liraglutide… read more here.
Keywords: glp; pharmacotherapy; management; glp gipr ... See more keywords
Enhanced Endosomal Signaling and Desensitization of GLP-1R vs GIPR in Pancreatic Beta Cells
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DOI: 10.1210/endocr/bqad028
Abstract: Abstract The incretin receptors, glucagon-like peptide-1 receptor (GLP-1R) and glucose-dependent insulinotropic polypeptide receptor (GIPR), are prime therapeutic targets for the treatment of type 2 diabetes (T2D) and obesity. They are expressed in pancreatic beta cells… read more here.
Keywords: beta; pancreatic beta; glp gipr; gipr ... See more keywords