Design of Xenopus GLP-1-Based Long-Acting Dual GLP-1/Y2 Receptor Agonists.
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DOI: 10.1021/acs.jmedchem.2c01385
Abstract: GLP-1 receptor (GLP-1R) and neuropeptide Y2 receptor (Y2R) dual agonists have shown great potential to treat obesity and type 2 diabetes (T2DM). We developed a multitarget strategy to design monomeric agonists based on Xenopus GLP-1… read more here.
Keywords: glp; xenopus glp; glp y2r; glp receptor ... See more keywords