Comparative effectiveness of SGLT2i versus GLP1-RA on cardiovascular outcomes in routine clinical practice.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2022.01.042
Abstract: BACKGROUND To investigate the comparative effectiveness of sodium-glucose cotransporter 2 inhibitors (SGLT2i) and glucagon-like peptide 1 receptor agonists (GLP1-RA) on cardiovascular outcomes in routine clinical practice, which have never been directly compared in head-to-head outcome… read more here.
Keywords: risk; cardiovascular outcomes; comparative effectiveness; glp1 cardiovascular ... See more keywords
Comparative effectiveness of a glucagon-like peptide-1 receptor agonist versus a dipeptidyl peptide-4 inhibitor on kidney and cardiovascular outcomes in routine clinical practice.
Sign Up to like & getrecommendations! Published in 2021 at "Kidney international"
DOI: 10.1016/j.kint.2021.10.033
Abstract: Whether glucagon-like peptide-1 receptor agonists (GLP1-RA) reduce detrimental kidney outcomes is uncertain. In secondary analyses, trials have shown consistent reductions in macroalbuminuria, but inconclusive results about kidney function decline. To help clarify this, we conducted… read more here.
Keywords: kidney; peptide; glp1; glucagon like ... See more keywords
A Germin-Like Protein GLP1 of Legumes Mediates Symbiotic Nodulation by Interacting with an Outer Membrane Protein of Rhizobia
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.03350-22
Abstract: This study is the first report to characterize a legume host plant protein to sense and interact with an outer membrane protein (OMP) of rhizobia. It can be speculated that GLP1 plays an essential role… read more here.
Keywords: outer membrane; nodulation; glp1; membrane protein ... See more keywords
Glucagon-like peptide 1 (GLP1) neurons provide highly collateralized axonal input to multiple brain regions
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5730137
Abstract: GLP1-immunopositive axons are present within a large number of subcortical brain regions in rats and mice. GLP1 neurons are activated/recruited by stress-related stimuli, and central GLP1 receptor signaling contributes to a variety of behavioral and… read more here.
Keywords: glp1 neurons; brain regions; glp1; physiology ... See more keywords
Glucagon-like peptide-1 receptor agonist (GLP1-RA) therapy in type 2 diabetes.
Sign Up to like & getrecommendations! Published in 2022 at "Australian journal of general practice"
DOI: 10.31128/ajgp-07-21-6057
Abstract: BACKGROUND Type 2 diabetes (T2D) is a national health priority. Its rising prevalence is accompanied by a high burden of diabetes-related complications, many of which are preventable. Numerous glucose-lowering medications have been developed in recent years with growing… read more here.
Keywords: glp1 ras; glp1; glucagon like; peptide receptor ... See more keywords
GLP-1 enhances hyperpolarization-activated currents of mouse cerebellar Purkinje cell in vitro
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2023.1126447
Abstract: Glucagon-like peptide-1 (GLP-1) is mainly secreted by preglucagonergic neurons in the nucleus tractus solitarius, which plays critical roles in regulation of neuronal activity in the central nervous system through its receptor. In the cerebellar cortex,… read more here.
Keywords: glp; purkinje cell; glp1; activity ... See more keywords
Improved systemic half-life of glucagon-like peptide-1-loaded carbonate apatite nanoparticles in rats
Sign Up to like & getrecommendations! Published in 2022 at "World Journal of Diabetes"
DOI: 10.4239/wjd.v13.i8.613
Abstract: BACKGROUND Glucagon-like peptide-1 (GLP1) is an endogenous peptide that regulates blood glucose level. But its susceptibility to rapid metabolic degradation limits its therapeutic use. AIM To prepare GLP1-encapsulated nanosize particle with controlled release property to… read more here.
Keywords: half life; glucagon like; glp1; peptide ... See more keywords