Differential regulation of ischemic limb vascularization and tumor growth by endothelial glutaredoxin-1
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DOI: 10.1016/j.freeradbiomed.2017.10.050
Abstract: Mechanisms for the lack of efficacy of anti-angiogenic strategies for cancer have not been elucidated. We previously demonstrated that up-regulated glutaredoxin-1 (Glrx) inhibited endothelial cell (EC) angiogenic properties. Glrx is a small cytosolic enzyme which… read more here.
Keywords: limb vascularization; glrx mice; ischemic limb; mice ... See more keywords