The role of hippocampal glial glutamate transporter (GLT‐1) in morphine‐induced behavioral responses
Sign Up to like & getrecommendations! Published in 2021 at "Brain and Behavior"
DOI: 10.1002/brb3.2323
Abstract: Opioid abuse modifies synaptic plasticity, which leads to behavioral changes, such as morphine dependence, but the mechanism remains poorly understood. Glial cells play an important role in the modulation of synaptic plasticity and are involved… read more here.
Keywords: glt; morphine dependence; glutamate; role hippocampal ... See more keywords
Neurosteroid dehydroepiandrosterone enhances activity and trafficking of astrocytic GLT‐1 via σ1 receptor‐mediated PKC activation in the hippocampal dentate gyrus of rats
Sign Up to like & getrecommendations! Published in 2017 at "Glia"
DOI: 10.1002/glia.23175
Abstract: Neurosteroid dehydroepiandrosterone (DHEA) has been reported to exert a potent neuroprotective effect against glutamate‐induced excitotoxicity. However, the underlying mechanism remains to be elucidated. One of the possible mechanisms may be an involvement of astrocytic glutamate… read more here.
Keywords: glt; dentate gyrus; activity; neurosteroid dehydroepiandrosterone ... See more keywords
Conditional Knockout of GLT-1 in Neurons Leads to Alterations in Aspartate Homeostasis and Synaptic Mitochondrial Metabolism in Striatum and Hippocampus
Sign Up to like & getrecommendations! Published in 2020 at "Neurochemical Research"
DOI: 10.1007/s11064-020-03000-7
Abstract: Expression of the glutamate transporter GLT-1 in neurons has been shown to be important for synaptic mitochondrial function in the cerebral cortex. Here we determined whether neuronal GLT-1 plays a similar role in the hippocampus… read more here.
Keywords: glt; synglt; glt neurons; metabolism ... See more keywords
Gelatin Loaded Titanium Dioxide and Silver Oxide Nanoparticles: Implication for Skin Tissue Regeneration.
Sign Up to like & getrecommendations! Published in 2020 at "Biological trace element research"
DOI: 10.1007/s12011-020-02489-x
Abstract: Treatment of burn wounds has many requirements to ensure wound closure with healthy tissue, increased vascularization, guarantee edema resolution, and control bacterial infection. We propose that titanium oxide (TiO2) nanoparticles (NPs) will be more efficient… read more here.
Keywords: glt; burn; ctrl glt; tissue ... See more keywords
LncRNA BIRF Promotes Brain Ischemic Tolerance Induced By Cerebral Ischemic Preconditioning Through Upregulating GLT-1 via Sponging miR-330-5p.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular neurobiology"
DOI: 10.1007/s12035-022-02841-3
Abstract: Long noncoding RNAs (lncRNAs) play an important regulatory role in various diseases. However, the role of lncRNAs in brain ischemic tolerance (BIT) induced by cerebral ischemic preconditioning (CIPC) is still unknown. The lncRNA profile of… read more here.
Keywords: birf; mir 330; glt; brain ... See more keywords
Norepinephrine-induced downregulation of GLT-1 mRNA in rat astrocytes.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.08.137
Abstract: AIM OF THE RESEARCH Glutamate transporter-1 (GLT-1; also known as excitatory amino acid transporter 2) plays an important role in the maintenance of glutamate homeostasis in the synaptic cleft. Downregulation of GLT-1 in the spinal… read more here.
Keywords: glt; glt mrna; spinal cord; downregulation glt ... See more keywords
Comparative sustainability evaluation of two engineered wood-based construction materials: Life cycle analysis of CLT versus GLT
Sign Up to like & getrecommendations! Published in 2021 at "Building and Environment"
DOI: 10.1016/j.buildenv.2021.108112
Abstract: Abstract The environmental emissions and energy from construction activity and building materials contributes significantly to a building's sustainability. Previous research dealing with wood or engineering wood's energy requirements compared to reinforced concrete and steel structures… read more here.
Keywords: clt; glt; wood based; wood ... See more keywords
Reciprocal communication between astrocytes and endothelial cells is required for astrocytic glutamate transporter 1 (GLT-1) expression
Sign Up to like & getrecommendations! Published in 2020 at "Neurochemistry International"
DOI: 10.1016/j.neuint.2020.104787
Abstract: Astrocytes have diverse functions that are supported by their anatomic localization between neurons and blood vessels. One of these functions is the clearance of extracellular glutamate. Astrocytes clear glutamate using two Na+-dependent glutamate transporters, GLT-1… read more here.
Keywords: glt; glt expression; notch; expression ... See more keywords
Guanosine Prevents against Glutamatergic Excitotoxicity in C. elegans
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2019.07.016
Abstract: Glutamatergic neurotransmission is present in most mammalian excitatory synapses and plays a key role in central nervous system homeostasis. When over-activated, it can induce excitotoxicity, which is present in several neuropathologies. The nucleoside guanosine (GUO),… read more here.
Keywords: glt; excitotoxicity; glutamatergic excitotoxicity; glt glt ... See more keywords
Fabrication and Characterization of Oleogel Stabilized by Gelatin-Polyphenol-Polysaccharides Nanocomplexes.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.8b02039
Abstract: The development of oleogel has attracted growing attention because of its health benefits and promising potential to substitute saturated or trans-fat. The present work reports a type of oleogel using the emulsion stabilized by gelatin… read more here.
Keywords: glt; oleogel stabilized; fabrication characterization; characterization oleogel ... See more keywords
Vitamin C Inhibits Ubiquitination of Glutamate Transporter 1 (GLT-1) in Astrocytes by Downregulating HECTD1.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.1c00845
Abstract: Excitatory neurotoxicity caused by the accumulation of glutamate in the synaptic cleft is an important cause of Parkinson's disease (PD). Astrocyte glutamate transporter 1 (GLT-1) is the main transporter responsible for transporting glutamate, and investigations… read more here.
Keywords: glt astrocytes; hectd1; expression; glt expression ... See more keywords