Guanosine Prevents against Glutamatergic Excitotoxicity in C. elegans
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DOI: 10.1016/j.neuroscience.2019.07.016
Abstract: Glutamatergic neurotransmission is present in most mammalian excitatory synapses and plays a key role in central nervous system homeostasis. When over-activated, it can induce excitotoxicity, which is present in several neuropathologies. The nucleoside guanosine (GUO),… read more here.
Keywords: glt; excitotoxicity; glutamatergic excitotoxicity; glt glt ... See more keywords
Heterogeneity of Astrocytic and Neuronal GLT-1 at Cortical Excitatory Synapses, as Revealed by its Colocalization With Na+/K+-ATPase α Isoforms.
Sign Up to like & getrecommendations! Published in 2018 at "Cerebral cortex"
DOI: 10.1093/cercor/bhy203
Abstract: GLT-1, the major glutamate transporter, is expressed at perisynaptic astrocytic processes (PAP) and axon terminals (AxT). GLT-1 is coupled to Na+/K+-ATPase (NKA) α1-3 isoforms, whose subcellular distribution and spatial organization in relationship to GLT-1 are… read more here.
Keywords: glt; atpase; neuronal glt; glt glt ... See more keywords