Pseudomonas aeruginosa Citrate Synthase GltA Influences Antibiotic Tolerance and the Type III Secretion System through the Stringent Response
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.03239-22
Abstract: Rising antimicrobial resistance imposes a severe threat to human health. It is urgent to develop novel antimicrobial strategies by understanding bacterial regulation of virulence and antimicrobial resistance determinants. ABSTRACT Carbohydrate metabolism plays essential roles in… read more here.
Keywords: antibiotic tolerance; glta; virulence; tolerance ... See more keywords
The Klebsiella pneumoniae citrate synthase gene, gltA, influences site specific fitness during infection
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1008010
Abstract: Klebsiella pneumoniae (Kp), one of the most common causes of healthcare-associated infections, increases patient morbidity, mortality, and hospitalization costs. Kp must acquire nutrients from the host for successful infection; however, the host is able to… read more here.
Keywords: citrate synthase; amino; infection; fitness ... See more keywords