Sucrose and the Lipid Environment Modulate Conformational Heterogeneity in the Glutamate Transporter Homologue Gltph
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DOI: 10.1016/j.bpj.2016.11.1049
Abstract: Gltph is a sodium dependent aspartate transporter that is structurally homologous to glutamate transporters; as a result, it provides a model for excitatory amino acid transporters (EAATs) that facilitate glutamate reuptake. Crystal structures suggest a… read more here.
Keywords: lipid environment; modulate conformational; gltph; glutamate ... See more keywords
Kinetic mechanism of coupled binding in sodium-aspartate symporter GltPh
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DOI: 10.7554/elife.37291
Abstract: Many secondary active membrane transporters pump substrates against concentration gradients by coupling their uptake to symport of sodium ions. Symport requires the substrate and ions to be always transported together. Cooperative binding of the solutes… read more here.
Keywords: mechanism; sodium aspartate; sodium; aspartate symporter ... See more keywords