Ferrochelatase π-helix: Implications from examining the role of the conserved π-helix glutamates in porphyrin metalation and product release.
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DOI: 10.1016/j.abb.2018.02.015
Abstract: Protoporphyrin ferrochelatase catalyzes the insertion of Fe2+ into protoporphyrin IX to form heme. To determine whether a conserved, active site π-helix contributes to the translocation of the metal ion substrate to the ferrochelatase-bound porphyrin substrate,… read more here.
Keywords: metalation; ferrochelatase helix; helix glutamates; helix ... See more keywords