Putrescine Intensifies Glu/GABA Exchange Mechanism and Promotes Early Termination of Seizures
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DOI: 10.3390/ijms23158191
Abstract: Endogenous anticonvulsant mechanisms represent a reliable and currently underdeveloped strategy against recurrent seizures and may recall novel original therapeutics. Here, we investigated whether the intensification of the astroglial Glu-GABA exchange mechanism by application of the… read more here.
Keywords: exchange mechanism; gaba; glu gaba; gaba exchange ... See more keywords
Dorsolateral Prefrontal Cortex Glutamate/Gamma-Aminobutyric Acid (GABA) Alterations in Clinical High Risk and First-Episode Schizophrenia: A Preliminary 7-T Magnetic Resonance Spectroscopy Imaging Study
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DOI: 10.3390/ijms232415846
Abstract: Converging lines of evidence suggest that an imbalance between excitation and inhibition is present in the dorsolateral prefrontal cortex (DLPFC) of schizophrenia (SCZ). Gamma-aminobutyric-acid (GABA) and, to a lesser extent, glutamate (Glu) abnormalities were reported… read more here.
Keywords: glu; dorsolateral prefrontal; spectroscopy; glu gaba ... See more keywords
Agarwood essential oil inhalation exerts antianxiety and antidepressant effects via the regulation of Glu/GABA system homeostasis
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DOI: 10.3892/br.2023.1598
Abstract: Depression and anxiety are common diseases that endanger the physical and mental health of individuals. Agarwood incense inhalation has been used as a traditional Chinese medicine for relaxation and to improve sleep for centuries. In… read more here.
Keywords: antidepressant effects; glu; glutamate; glu gaba ... See more keywords