Novel side reaction accompanying cyclization of Glu(R1)‐Glu(R2) dipeptides via lactamization of the Glu(R1) residue
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DOI: 10.1002/psc.3074
Abstract: A series of linear peptides with the general formula H‐Glu(R1)‐Glu(R2)‐OH was subjected to cyclization under standard conditions. Formation of respective 2,5‐diketopiperazines was accompanied by transformation of the N‐terminal Glu(R1) to pyroglutamic acid residue. Even in… read more here.
Keywords: lactamization; side reaction; novel side; glu glu ... See more keywords
Synthesis and gelation capability of mono- and disubstituted cyclo(L-Glu-L-Glu) derivatives with tyramine, tyrosine and phenylalanine
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DOI: 10.1007/s00396-017-4120-y
Abstract: A series of mono- and disubstituted glutamic cyclic dipeptide derivatives (cyclo(L-Glu-Glu)s) with tyramine, tyrosine, and phenylalanine (3–12) were synthesized and investigated as organo- and hydrogelators. Unexpectedly, both tyramine mono- and disubstituted cyclo(L-Glu-Glu)s showed no gelation… read more here.
Keywords: mono disubstituted; glu glu; tyrosine phenylalanine; glu ... See more keywords
Synthesis and Sensory Characteristics of Kokumi γ-[Glu]n-Phe in the Presence of Glutamine and Phenylalanine: Glutaminase from Bacillus amyloliquefaciens or Aspergillus oryzae as the Catalyst.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.7b03419
Abstract: The transpeptidase activity of glutaminase from Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO) to yield γ-[Glu]n-Phe peptides were verified for the first time. In the presence of Gln and Phe, γ-Glu-Phe and γ-Glu-γ-Glu-Phe were synthesized… read more here.
Keywords: phe glu; glutaminase bacillus; glu phe; glu glu ... See more keywords
THE EFFECT OF HMW-GS ON GLU-A1, GLU-B1, GLU-D1 IN SOME LOCAL BREAD (Triticum aestivum L.) WHEAT GENOTYPES
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DOI: 10.15666/aeer/1704_1022910238
Abstract: Wheat gluten proteins are extremely important proteins in terms of quality. Glutenin from the sub-units of gluten, because of the multi-polymer structure is effective in the rheological properties of the dough. In the study, samples… read more here.
Keywords: wheat genotypes; quality; wheat; glu glu ... See more keywords
The Glutathione Metabolite γ-Glutamyl-Glutamate Partially Activates Glutamate NMDA Receptors in Central Neurons With Higher Efficacy for GluN2B-Containing Receptors
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.794680
Abstract: Gamma-L-glutamyl-L-glutamate (γ-Glu-Glu) was synthetized and further characterized for its activity on cultured neurons. We observed that γ-Glu-Glu elicited excitatory effects on neurons likely by activating mainly the N-methyl-D-aspartate (NMDA) receptors. These effects were dependent on… read more here.
Keywords: glu; nmda receptors; glu glu; glutamyl glutamate ... See more keywords
Heterologous expression, purification and biochemical characterization of a glutamate racemase (MurI) from Streptococcus mutans UA159
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DOI: 10.7717/peerj.8300
Abstract: Background Glutamate racemase (MurI) is a cofactor-independent enzyme that is essential to the bacterial peptidoglycan biosynthesis pathway and has therefore been considered an attractive target for the development of antimicrobial drugs. While in our previous… read more here.
Keywords: glu glu; mutans ua159; glutamate racemase; glu ... See more keywords