Hippocampal amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid GluA1 (AMPA GluA1) receptor subunit involves in learning and memory improvement following treatment with Centella asiatica extract in adolescent rats
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DOI: 10.1002/brb3.1093
Abstract: Centella asiatica is an herbal plant that contains phytochemicals that are widely believed to have positive effects on cognitive function. The adolescent stage is a critical development period for the maturation of brain processes that… read more here.
Keywords: glua1; asiatica; learning memory; asiatica extract ... See more keywords
Enriched environment ameliorates postsurgery sleep deprivation-induced cognitive impairments through the AMPA receptor GluA1 subunit.
Sign Up to like & getrecommendations! Published in 2023 at "Brain and behavior"
DOI: 10.1002/brb3.2992
Abstract: BACKGROUND As a common postsurgery complication, sleep deprivation (SD) can severely deteriorate the cognitive function of patients. Enriched environment (EE) exposure can increase children's cognitive ability, and whether EE exposure could be utilized to alleviate… read more here.
Keywords: enriched environment; induced cognitive; sleep deprivation; cognitive impairments ... See more keywords
GluA1 in Central Amygdala Promotes Opioid Use and Reverses Inhibitory Effect of Pain
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DOI: 10.1016/j.neuroscience.2019.11.032
Abstract: Increasing evidence suggests that long-term opioids and pain induce similar adaptive changes in the brain's reward circuits, however, how pain alters the addictive properties of opioids remains poorly understood. In this study using a rat… read more here.
Keywords: glua1; morphine intake; opioid use; pain ... See more keywords
Reinforcement Rate and the Balance Between Excitatory and Inhibitory Learning: Insights From Deletion of the GluA1 AMPA Receptor Subunit
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DOI: 10.1037/xan0000336
Abstract: Conditioned responding is sensitive to reinforcement rate. This rate-sensitivity is impaired in genetically modified mice that lack the GluA1 subunit of the AMPA receptor. A time-dependent application of the Rescorla–Wagner learning rule can be used… read more here.
Keywords: reinforcement rate; sensitivity; inhibitory learning; rate ... See more keywords
Net decrease in spine-surface GluA1-containing AMPA receptors after post-learning sleep in the adult mouse cortex
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DOI: 10.1038/s41467-021-23156-2
Abstract: The mechanisms by which sleep benefits learning and memory remain unclear. Sleep may further strengthen the synapses potentiated by learning or promote broad synaptic weakening while protecting the newly potentiated synapses. We tested these ideas… read more here.
Keywords: glua1; net decrease; post learning; learning sleep ... See more keywords
Regulation of GluA1 phosphorylation by d‐amphetamine and methylphenidate in the cerebellum
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DOI: 10.1111/adb.12995
Abstract: Prescription stimulants, such as d‐amphetamine or methylphenidate are used to treat suffering from attention‐deficit hyperactivity disorder (ADHD). They potently release dopamine (DA) and norepinephrine (NE) and cause phosphorylation of the α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid (AMPA) receptor subunit… read more here.
Keywords: glua1; amphetamine methylphenidate; phosphorylation; glua1 phosphorylation ... See more keywords
Visualization of Exo- and Endocytosis of AMPA Receptors During Hippocampal Synaptic Plasticity Around Postsynaptic-Like Membrane Formed on Glass Surface
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2018.00442
Abstract: Regulation of exo- and endocytosis of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptor (AMPAR) plays a critical role in the expression of synaptic plasticity such as long-term potentiation (LTP) and long-term depression (LTD) at excitatory central synapses.… read more here.
Keywords: glua1; exo endocytosis; endocytosis; synaptic plasticity ... See more keywords
Activation of Protein Kinase G After Repeated Cocaine Administration Is Necessary for the Phosphorylation of α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptor GluA1 at Serine 831 in the Rat Nucleus Accumbens
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2018.00263
Abstract: Phosphorylation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors in the striatum plays a crucial role in regulating the receptor-coupled signaling cascades leading to behavioral changes associated with psychostimulant exposure. The present study determined if activation of protein… read more here.
Keywords: glua1; repeated cocaine; receptor; phosphorylation ... See more keywords