Hepatic Glucagon Action - Beyond Glucose Mobilization.
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DOI: 10.1152/physrev.00028.2023
Abstract: Glucagon's ability to promote hepatic glucose production has been known for over a century with initial observations touting this hormone as a diabetogenic agent. However, glucagon receptor agonism (when balanced with an incretin, including glucagon-like… read more here.
Keywords: hepatic glucagon; glucagon action; action beyond; hormone ... See more keywords
1634-P: Chip Mediates Glucagon Action on Hepatic Glucose Production via Regulating SMAD3 Ubiquitination
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DOI: 10.2337/db25-1634-p
Abstract: Introduction and Objective: Glucagon promotes hepatic glucose production (HGP) to maintain glucose homeostasis, whereas augmented glucagon action on HGP resulting in hyperglycemia in obesity and type 2 diabetes (T2D). However, the underlying mechanisms of enhanced… read more here.
Keywords: obesity; glucagon action; hgp; chip ... See more keywords