Aspirin suppresses hepatic glucagon signaling through decreasing production of thromboxane A2.
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DOI: 10.1210/endocr/bqac217
Abstract: Excessive hepatic glucose production (HGP) is a major cause of fasting hyperglycemia in diabetes and antihyperglycemic therapy takes center stage. Nonsteroidal anti-inflammatory drugs (NSAIDs), such as acetylsalicylic acid(Aspirin), reduce hyperglycemia caused by unrestrained gluconeogenesis in… read more here.
Keywords: glucagon signaling; thromboxane; production; gluconeogenesis ... See more keywords