The β-1,3-glucan synthase gene GFGLS2 plays major roles in mycelial growth and polysaccharide synthesis in Grifola frondosa.
Sign Up to like & getrecommendations! Published in 2021 at "Applied microbiology and biotechnology"
DOI: 10.1007/s00253-021-11734-9
Abstract: β-1,3-Glucans are well-known biological and health-promoting compounds in edible fungi. Our previous results characterized a glucan synthase gene (GFGLS) of Grifola frondosa for the first time to understand its role in mycelial growth and glucan… read more here.
Keywords: gfgls2; synthase gene; mycelial growth; glucan synthase ... See more keywords
Influence of α-1,3-glucan synthase gene agsE on protoplast formation for transformation of Aspergillus luchuensis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of bioscience and bioengineering"
DOI: 10.1016/j.jbiosc.2019.01.018
Abstract: Aspergillus luchuensis NBRC4314 recently underwent genome sequencing. We have not used the frequently used protoplast-polyethylene glycol (PEG) method but have used agrobacterium-mediated transformation (AMT) to genetically engineer this strain because it was difficult to generate… read more here.
Keywords: glucan synthase; luchuensis; protoplast formation; transformation ... See more keywords
Length specificity and polymerization mechanism of (1,3)-β-D-glucan synthase in fungal cell wall biosynthesis.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemistry"
DOI: 10.1021/acs.biochem.9b00896
Abstract: (1,3)-β-D-Glucan synthase (GS) catalyzes formation of the linear (1,3)-β-D-glucan in the fungal cell wall, and is a tar-get of clinically approved antifungal antibiotics. The catalytic subunit of GS, FKS protein, does not exhibit significant sequence… read more here.
Keywords: length; polymerization; synthase; mechanism ... See more keywords
CRISPR-Cas9/Safe Harbor-Targeted Overexpression of Glucan Synthase Gene CmGls in Edible Mushroom Cordyceps militaris.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.5c01310
Abstract: The membrane-integrated β-1,3-glucan synthase is the key enzyme involved in the biosynthesis of the core component β-1,3-glucan of the fungal cell wall. To date, the precise and targeted insertion of the β-1,3-glucan synthase gene into… read more here.
Keywords: synthase; synthase gene; glucan synthase; gene cmgls ... See more keywords
Fungal β-1,3-Glucan Synthase: A Review of Structure, Mechanism, and Regulation.
Sign Up to like & getrecommendations! Published in 2025 at "FEMS yeast research"
DOI: 10.1093/femsyr/foaf071
Abstract: Abstract Fungal β-1,3-glucan synthase (Fks) plays a central role in synthesizing β-1,3-glucan, the main structural polysaccharide of fungal cell walls, and serves as a key target for antifungal drugs, such as echinocandins and ibrexafungerp. Recent… read more here.
Keywords: synthase; structure; glucan synthase; synthase review ... See more keywords
Rice GLUCAN SYNTHASE-LIKE5 promotes anther callose deposition to maintain meiosis initiation and progression
Sign Up to like & getrecommendations! Published in 2022 at "Plant Physiology"
DOI: 10.1093/plphys/kiac488
Abstract: Abstract Callose is a plant cell wall polysaccharide whose deposition is spatiotemporally regulated in various developmental processes and environmental stress responses. The appearance of callose in premeiotic anthers is a prominent histological hallmark for the… read more here.
Keywords: meiosis; deposition; rice; glucan synthase ... See more keywords
Epistasis at the cell surface: what is the role of Erg3 loss-of-function in acquired echinocandin resistance?
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DOI: 10.1128/mbio.01419-25
Abstract: ABSTRACT Echinocandins, which target the fungal β-1,3-glucan synthase (Fks), are essential for treating invasive fungal infections, yet resistance is increasingly reported. While resistance typically arises through mutations in Fks hotspots, emerging evidence suggests a contributing… read more here.
Keywords: resistance; echinocandin resistance; glucan synthase; loss function ... See more keywords
Effects of β-1,6-Glucan Synthase Gene (FfGS6) Overexpression on Stress Response and Fruit Body Development in Flammulina filiformis
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13101753
Abstract: β-1, 6-glucan synthase is a key enzyme of β-1, 6-glucan synthesis, which plays a vital role in the cell wall cross-linking of fungi. However, the role of the β-1, 6-glucan synthase gene in the development… read more here.
Keywords: synthase gene; stress response; glucan synthase; gene ... See more keywords