Glucosylceramide modifies the LPS-induced inflammatory response in macrophages and the orientation of the LPS/TLR4 complex in silico
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DOI: 10.1038/s41598-018-31926-0
Abstract: Toll-like receptor 4 (TLR4) is activated by bacterial lipopolysaccharide (LPS), which drives the production of proinflammatory cytokines. Earlier studies have indicated that cholesterol- and glycosphingolipid-rich subregions of the plasma membrane (lipid domains) are important for… read more here.
Keywords: lps induced; glucer; lps tlr4; inflammatory response ... See more keywords