Plasma metabolomic profile varies with glucocorticoid dose in patients with congenital adrenal hyperplasia
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DOI: 10.1038/s41598-017-17220-5
Abstract: Glucocorticoid replacement therapy is the mainstay of treatment for congenital adrenal hyperplasia (CAH) but has a narrow therapeutic index and dose optimisation is challenging. Metabolomic profiling was carried out on plasma samples from 117 adults… read more here.
Keywords: glucocorticoid dose; adrenal hyperplasia; plasma metabolomic; congenital adrenal ... See more keywords
Construction and evaluation of glucocorticoid dose prediction model based on genetic and clinical characteristics of patients with systemic lupus erythematosus
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DOI: 10.1177/03946320251331791
Abstract: Currently, no glucocorticoid dose prediction model is available for clinical practice. This study aimed to utilise machine learning techniques to develop and validate personalised dosage models. Participants were patients with SLE who were registered at… read more here.
Keywords: dose prediction; glucocorticoid dose; prediction; model ... See more keywords
No need of glucocorticoid dose adjustment in patients with adrenal insufficiency before COVID-19 vaccine.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of endocrinology"
DOI: 10.1530/eje-21-1236
Abstract: Objective Coronavirus disease-2019 (COVID-19) causes acute respiratory distress syndrome. Patients with adrenal insufficiency (AI) may develop severe complications due to this infection and should undergo COVID-19 vaccination; however, there is no consensus about the management… read more here.
Keywords: need glucocorticoid; patients adrenal; covid; vaccine ... See more keywords