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Published in 2019 at "Cell Reports"
DOI: 10.1016/j.celrep.2019.08.088
Abstract: Summary The glucocorticoid receptor (GR) acts as a ubiquitous cortisol-dependent transcription factor (TF). To identify co-factors, we used protein-fragment complementation assays and found that GR recognizes FLI1 and additional ETS family proteins, TFs relaying proliferation…
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Keywords:
treatment;
ets proteins;
glucocorticoid receptors;
proteins bind ... See more keywords
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Published in 2017 at "Neurobiology of Learning and Memory"
DOI: 10.1016/j.nlm.2017.08.004
Abstract: Ample evidence demonstrates that fear learning contributes significantly to many anxiety pathologies including post-traumatic stress disorder (PTSD). The endocannabinoid (eCB) system may offer therapeutic benefits for PTSD and it is a modulator of the hypothalamic…
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Keywords:
consolidation;
glucocorticoid receptors;
traumatic event;
win55 212 ... See more keywords
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Published in 2022 at "Expert Opinion on Therapeutic Targets"
DOI: 10.1080/14728222.2022.2032650
Abstract: ABSTRACT Background Glucocorticoid receptors (GRs) and mineralocorticoid receptors (MRs) are involved in neuronal excitability, neurogenesis, and neuroinflammation. However, the roles of GRs and MRs in epilepsy in focal cortical dysplasia II (FCDII) have not been…
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Keywords:
focal cortical;
model rats;
fcdii patients;
glucocorticoid receptors ... See more keywords
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Published in 2017 at "International Journal of Breast Cancer"
DOI: 10.1155/2017/1403054
Abstract: The role of estrogen and progesterone receptors in breast cancer biology is well established. In contrast, other steroid hormones are less well studied. Glucocorticoids (GCs) are known to play a role in mammary development and…
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Keywords:
role mammary;
breast;
epithelium;
receptors breast ... See more keywords
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Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0204980
Abstract: Previous research has shown that fibroblast growth factor 2 protein (FGF2) can act as an anxiolytic and anti-depressive agent in rodents. Levels of hippocampal FGF2 and FGF2 receptors are decreased in post-mortem brains of individuals…
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Keywords:
fgf2;
effects fluoxetine;
fibroblast growth;
glucocorticoid receptors ... See more keywords