Extensive epigenomic integration of the glucocorticoid response in primary human monocytes and in vitro derived macrophages
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-39395-9
Abstract: Glucocorticoid receptor is a transcription factor that is ubiquitously expressed. Glucocorticoids are circadian steroids that regulate a wide range of bodily functions, including immunity. Here we report that synthetic glucocorticoids affect 1035 mRNAs in isolated… read more here.
Keywords: epigenomic integration; glucocorticoid response; response; extensive epigenomic ... See more keywords
The relative speed of the glucocorticoid stress response varies independently of scope and is predicted by environmental variability and longevity across birds.
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DOI: 10.1101/2021.10.18.464833
Abstract: The acute glucocorticoid response is a key mediator of the coordinated vertebrate response to unpredictable challenges. Rapid glucocorticoid increases initiate changes that allow animals to cope with stressors. The scope of the glucocorticoid response —… read more here.
Keywords: speed; relative speed; glucocorticoid response; speed glucocorticoid ... See more keywords
Simulating physiological flexibility in the acute glucocorticoid response to stressors reveals limitations of current empirical approaches
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DOI: 10.7717/peerj.14039
Abstract: Wild animals often experience unpredictable challenges that demand rapid and flexible responses. The glucocorticoid mediated stress response is one of the major systems that allows vertebrates to rapidly adjust their physiology and behavior. Given its… read more here.
Keywords: glucocorticoid response; acute glucocorticoid; simulation; physiological flexibility ... See more keywords