TLR3 augments glucocorticoid-synthetic enzymes expression in epidermal keratinocytes; Implications of glucocorticoid metabolism in rosacea epidermis.
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DOI: 10.1016/j.jdermsci.2020.08.011
Abstract: BACKGROUND While most skin diseases benefit from topical steroids, rosacea symptoms are exacerbated by topical steroids. In the rosacea pathogenesis, abnormal innate immune mechanisms including overexpression of the Toll-like receptor (TLR) have been proposed. However,… read more here.
Keywords: synthetic enzymes; tlr3; epidermal keratinocytes; glucocorticoid synthetic ... See more keywords