Glucocorticoids modulate multidrug resistance transporters in the first trimester human placenta
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DOI: 10.1111/jcmm.13646
Abstract: The placental multidrug transporters, P‐glycoprotein (P‐gp, encoded by ABCB1) and breast cancer resistance protein (BCRP, ABCG2) protect the foetus from exposure to maternally derived glucocorticoids, toxins and xenobiotics. During pregnancy, maternal glucocorticoid levels can be… read more here.
Keywords: trimester human; bcrp; human placenta; glucocorticoids modulate ... See more keywords