DMT efficiently inhibits hepatic gluconeogenesis by regulating the Gαq signaling pathway.
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DOI: 10.1530/jme-17-0121
Abstract: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease with complicated pathogenesis and targeting gluconeogenesis inhibition is a promising strategy for anti-diabetic drug discovery. G protein-coupled receptors (GPCRs) are classified as distinct families by… read more here.
Keywords: protein; regulating signaling; gluconeogenesis regulating; signaling pathway ... See more keywords