The UDP-glucose ceramide glycosyltransferase (UGCG) and the link to multidrug resistance protein 1 (MDR1)
Sign Up to like & getrecommendations! Published in 2018 at "BMC Cancer"
DOI: 10.1186/s12885-018-4084-4
Abstract: The UDP-glucose ceramide glycosyltransferase (UGCG) is a key enzyme in the sphingolipid metabolism by generating glucosylceramide (GlcCer), the precursor for all glycosphingolipids (GSL), which are essential for proper cell function. Interestingly, the UGCG is also… read more here.
Keywords: protein; udp glucose; resistance; glucose ceramide ... See more keywords
Role of UDP-glucose ceramide glucosyltransferase in venous malformation
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DOI: 10.3389/fcell.2023.1178045
Abstract: Venous malformation (VM) results from the abnormal growth of the vasculature; however, the detailed molecular mechanism remains unclear. As a glycosyltransferase, UDP-glucose ceramide glucosyltransferase (UGCG) is localized to the Golgi body and is a key… read more here.
Keywords: ceramide glucosyltransferase; glucose ceramide; udp glucose; venous malformation ... See more keywords