SCFβ‐TrCP ubiquitinates CHK1 in an AMPK‐dependent manner in response to glucose deprivation
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12403
Abstract: The ATR/CHK1 pathway is a key effector of cellular response to DNA damage and therefore is a critical regulator of genomic stability. While the ATR/CHK1 pathway is often inactivated by mutations, CHK1 itself is rarely… read more here.
Keywords: chk1; response glucose; glucose deprivation; deprivation ... See more keywords
Cooperation of HIF‐ and NCAM‐mediated mechanisms in cell viability of hippocampal cultures after oxygen–glucose deprivation
Sign Up to like & getrecommendations! Published in 2017 at "Cell Biology International"
DOI: 10.1002/cbin.10825
Abstract: Neurodegenerative diseases of different genesis are the result of cellular damages including those caused by oxygen and glucose deficit. Neuronal survival or death in brain pathologies depends on a variety of interrelated molecular mechanisms. A… read more here.
Keywords: cell viability; viability; glucose deprivation; oxygen glucose ... See more keywords
Asiaticoside attenuates oxygen–glucose deprivation/reoxygenation‐caused injury of cardiomyocytes by inhibiting autophagy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4424
Abstract: Asiaticoside is a natural triterpene compound derived from Centella asiatica, possessing confirmed cardioprotective property. However, the roles of asiaticoside in regulating oxygen–glucose deprivation/reoxygenation (OGD/R)‐caused cardiomyocyte dysfunction remain largely obscure. Human cardiomyocyte AC16 cells were stimulated… read more here.
Keywords: deprivation reoxygenation; cytotoxicity; glucose deprivation; oxygen glucose ... See more keywords
microRNA‐186 alleviates oxygen‐glucose deprivation/reoxygenation‐induced injury by directly targeting hypoxia‐inducible factor‐1α
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22752
Abstract: Previous studies have suggested that microRNA‐186 (miR‐186) can be induced under hypoxic conditions, and is associated with apoptosis. This study was undertaken to explore the exact role of this microRNA (miRNA) in the apoptotic death… read more here.
Keywords: microrna 186; glucose deprivation; oxygen glucose; mir 186 ... See more keywords
Higenamine protects neuronal cells from oxygen‐glucose deprivation/reoxygenation‐induced injury
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27656
Abstract: Higenamine, a plant‐based alkaloid, exhibits various properties, such as antiapoptotic and antioxidative effects. Previous studies proved that higenamine possesses potential therapeutic effects for ischemia/reperfusion (I/R) injuries. However, the role of higenamine in cerebral I/R injury… read more here.
Keywords: neuronal cells; higenamine; glucose deprivation; higenamine protects ... See more keywords
Sertoli cell adaptation to glucose deprivation: Potential role of AMPK in the regulation of lipid metabolism
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.30399
Abstract: Sertoli cells (SCs) provide an adequate environment for germ cell development. SCs possess unique features that meet germ cells' metabolic demands: they produce lactate from glucose, which is delivered as energy substrate to germ cells.… read more here.
Keywords: cell; sertoli; glucose deprivation; lipid metabolism ... See more keywords
Mitochondrial numbers increase during glucose deprivation in the slime mold Physarum polycephalum
Sign Up to like & getrecommendations! Published in 2019 at "Protoplasma"
DOI: 10.1007/s00709-019-01410-1
Abstract: Glucose deprivation in the slime mold Physarum polycephalum leads to a specific morphotype, a highly motile mesoplasmodium. We investigated the ultrastructure of both mesoplasmodia and non-starved plasmodia and found significantly increased numbers of mitochondria in… read more here.
Keywords: slime mold; deprivation slime; glucose deprivation; mold physarum ... See more keywords
LncRNA MALAT1 Promotes Oxygen-Glucose Deprivation and Reoxygenation Induced Cardiomyocytes Injury Through Sponging miR-20b to Enhance beclin1-Mediated Autophagy
Sign Up to like & getrecommendations! Published in 2019 at "Cardiovascular Drugs and Therapy"
DOI: 10.1007/s10557-019-06902-z
Abstract: LncRNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is reported to be highly expressed in myocardial I/R injury and closely related to autophagy. However, the exact biological role of MALAT1 and its underlying mechanism in myocardial… read more here.
Keywords: beclin1; glucose deprivation; malat1; oxygen glucose ... See more keywords
Neuroprotective Effect of Oxysophocarpine by Modulation of MAPK Pathway in Rat Hippocampal Neurons Subject to Oxygen–Glucose Deprivation and Reperfusion
Sign Up to like & getrecommendations! Published in 2017 at "Cellular and Molecular Neurobiology"
DOI: 10.1007/s10571-017-0501-5
Abstract: Oxysophocarpine (OSC), an alkaloid isolated from Sophora flavescens Ait, has been traditionally used as a medicinal agent based on the observed pharmacological effects. In this study, the direct effect of OSC against neuronal injuries induced… read more here.
Keywords: hippocampal neurons; glucose deprivation; oxysophocarpine; effect ... See more keywords
The p38/CYLD Pathway is Involved in Necroptosis Induced by Oxygen-glucose Deprivation Combined with ZVAD in Primary Cortical Neurons
Sign Up to like & getrecommendations! Published in 2017 at "Neurochemical Research"
DOI: 10.1007/s11064-017-2244-6
Abstract: Recently, necroptosis, a form of programmed necrosis, has been widely studied. It has previously been shown that knockout of lysine 63 deubiquitinase CYLD significantly inhibits necroptosis in other cell lines, and serum response factor (SRF)… read more here.
Keywords: ogd zvad; necroptosis induced; glucose deprivation; necroptosis ... See more keywords
Knockdown of TRIM32 Protects Hippocampal Neurons from Oxygen–Glucose Deprivation-Induced Injury
Sign Up to like & getrecommendations! Published in 2019 at "Neurochemical Research"
DOI: 10.1007/s11064-019-02857-7
Abstract: Tripartite motif 32 (TRIM32) is a member of TRIM family that plays a potential role in neural regeneration. However, the biological function of TRIM32 in cerebral ischemia reperfusion injury has not been investigated. In the… read more here.
Keywords: hippocampal neurons; knockdown trim32; glucose deprivation; oxygen glucose ... See more keywords