The relationships between hemoglobin and insulin resistance, glucose effectiveness, and first- and second-phase insulin secretion in adult Chinese.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of endocrinology and metabolism"
DOI: 10.20945/2359-3997000000169
Abstract: OBJECTIVE We denote the four major factors related to the development of type 2 diabetes (T2D) as "diabetes factor" (DF); increased insulin resistance (IR); decreased glucose effectiveness (GE); and the first-and-second-phase of insulin secretion (FPIS,… read more here.
Keywords: insulin; fpis spis; glucose effectiveness; insulin secretion ... See more keywords
Correcting Postprandial Hyperglycemia in Zucker Diabetic Fatty Rats With an SGLT2 Inhibitor Restores Glucose Effectiveness in the Liver and Reduces Insulin Resistance in Skeletal Muscle
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DOI: 10.2337/db16-1410
Abstract: Ten-week-old Zucker diabetic fatty (ZDF) rats at an early stage of diabetes embody metabolic characteristics of obese human patients with type 2 diabetes, such as severe insulin and glucose intolerance in muscle and the liver,… read more here.
Keywords: zucker diabetic; diabetic fatty; glucose effectiveness; muscle ... See more keywords
Central KATP Channels Modulate Glucose Effectiveness in Humans and Rodents
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DOI: 10.2337/db19-1256
Abstract: Hyperglycemia is a potent regulator of endogenous glucose production (EGP). Loss of this “glucose effectiveness” is a major contributor to elevated plasma glucose concentrations in type 2 diabetes (T2D). KATP channels in the central nervous… read more here.
Keywords: glucose effectiveness; katp channels; katp; hyperglycemia ... See more keywords
An Analysis of Glucose Effectiveness in Subjects With or Without Type 2 Diabetes via Hierarchical Modeling
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DOI: 10.3389/fendo.2021.641713
Abstract: Glucose effectiveness, defined as the ability of glucose itself to increase glucose utilization and inhibit hepatic glucose production, is an important mechanism maintaining normoglycemia. We conducted a minimal modeling analysis of glucose effectiveness at zero… read more here.
Keywords: modeling analysis; analysis glucose; glucose effectiveness; analysis ... See more keywords
Lower Glucose Effectiveness Is Associated with Postprandial Hyperglycemia in Obese/Overweight Men, Independently of Insulin Secretion
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DOI: 10.3390/metabo12111022
Abstract: The role of glucose effectiveness on postprandial hyperglycemia in daily life is not fully studied. Here, we examined the association between SgIo, an index of glucose effectiveness calculated from a 75 g oral glucose tolerance… read more here.
Keywords: postprandial hyperglycemia; overweight men; glucose effectiveness; lower glucose ... See more keywords