Mismatch between GLUTs and glucose levels causes neuronal damage during glucose fluctuations.
Sign Up to like & getrecommendations! Published in 2018 at "Medical hypotheses"
DOI: 10.1016/j.mehy.2018.01.010
Abstract: Abnormal glucose levels damage the central nervous system, especially in case of rapid fluctuations. Even a single episode of glucose reperfusion can result in overt impairment of neurons. Oxidative stress plays an important role in… read more here.
Keywords: neuronal damage; glucose levels; mismatch gluts; glucose fluctuations ... See more keywords
Glucose fluctuations promote vascular BK channels dysfunction via PKCα/NF-κB/MuRF1 signaling.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of molecular and cellular cardiology"
DOI: 10.1016/j.yjmcc.2020.05.021
Abstract: Glucose fluctuations may contribute to large conductance calcium activated potassium (BK) channel dysfunction. However, the underlying mechanisms remain elusive. The aim of this study was to investigate the molecular mechanisms involved in BK channel dysfunction… read more here.
Keywords: dysfunction via; dysfunction; glucose fluctuations; pkc murf1 ... See more keywords
Detecting Glucose Fluctuations in the Campylobacter jejuni N-Glycan Structure.
Sign Up to like & getrecommendations! Published in 2021 at "ACS chemical biology"
DOI: 10.1021/acschembio.1c00498
Abstract: Campylobacter jejuni is a significant cause of human gastroenteritis worldwide, and all strains express an N-glycan that is added to at least 80 different proteins. We characterized 98 C. jejuni isolates from infants from 7… read more here.
Keywords: campylobacter jejuni; detecting glucose; glucose fluctuations; galnac galnac ... See more keywords
Molecular Mechanisms of Glucose Fluctuations on Diabetic Complications
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2019.00640
Abstract: Accumulating evidence indicates the occurrence and development of diabetic complications relates to not only constant high plasma glucose, but also glucose fluctuations which affect various kinds of molecular mechanisms in various target cells and tissues.… read more here.
Keywords: mechanisms glucose; fluctuations diabetic; glucose fluctuations; protein kinase ... See more keywords