Impact of Obesity on Postprandial Triglyceride Contribution to Glucose Homeostasis, Assessed with a Semimechanistic Model
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.2604
Abstract: The integrated glucose‐insulin model is a semimechanistic model describing glucose and insulin after a glucose challenge. Similarly, a semiphysiologic model of the postprandial triglyceride (TG) response in chylomicrons and VLDL‐V6 was recently published. We have… read more here.
Keywords: glucose insulin; postprandial triglyceride; model; obese obese ... See more keywords
Maternal blood glucose level and offspring glucose–insulin homeostasis: what is the role of offspring adiposity?
Sign Up to like & getrecommendations! Published in 2020 at "Diabetologia"
DOI: 10.1007/s00125-020-05294-2
Abstract: Aims/hypothesis The aim of this work was to investigate the association of maternal HbA 1c during mid-pregnancy with biomarkers of glucose–insulin homeostasis during early childhood (4–7 years of age) and to assess whether and how offspring… read more here.
Keywords: insulin homeostasis; offspring adiposity; age; offspring glucose ... See more keywords
Effects of breaking up prolonged sitting following low and high glycaemic index breakfast consumption on glucose and insulin concentrations
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Applied Physiology"
DOI: 10.1007/s00421-017-3610-4
Abstract: PurposeBreaking up prolonged sitting can attenuate the postprandial rise in glucose and insulin. Whether such effects are dependent of the glycaemic index (GI) of the consumed carbohydrate is unknown. This study examined the acute effects… read more here.
Keywords: insulin concentrations; prolonged sitting; breakfast; glucose insulin ... See more keywords
Pretreatment with glucose–insulin–potassium improves ventricular performances after coronary artery bypass surgery: a randomized controlled trial
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Monitoring and Computing"
DOI: 10.1007/s10877-019-00280-5
Abstract: Heart failure is the main cause of poor outcome following open heart surgery and experimental studies have demonstrated that glucose–insulin–potassium (GIK) infusion exerts cardioprotective effects by reducing myocardial ischemia–reperfusion injuries. This randomized controlled trial was… read more here.
Keywords: surgery; insulin potassium; randomized controlled; coronary artery ... See more keywords
The link between insulin resistance parameters and serum uric acid is mediated by adiposity.
Sign Up to like & getrecommendations! Published in 2018 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2017.12.033
Abstract: BACKGROUND AND AIMS Conflicting results suggest a link between serum uric acid (SUA), inflammation and glucose/insulin homeostasis; however, the role of adiposity in this relationship is not clear. Therefore, we evaluated the role of different… read more here.
Keywords: insulin; insulin homeostasis; adiposity; inflammation glucose ... See more keywords
Model individualization for artificial pancreas
Sign Up to like & getrecommendations! Published in 2019 at "Computer methods and programs in biomedicine"
DOI: 10.1016/j.cmpb.2016.06.006
Abstract: BACKGROUND AND OBJECTIVE The inter-subject variability characterizing the patients affected by type 1 diabetes mellitus makes automatic blood glucose control very challenging. Different patients have different insulin responses, and a control law based on a… read more here.
Keywords: control; model individualization; model; artificial pancreas ... See more keywords
AMP-activated protein kinase α1 in Megalobrama amblycephala: Molecular characterization and the transcriptional modulation by nutrient restriction and glucose and insulin loadings.
Sign Up to like & getrecommendations! Published in 2018 at "General and comparative endocrinology"
DOI: 10.1016/j.ygcen.2018.05.030
Abstract: This study aimed to characterize the full-length cDNA of AMP-activated protein kinase α1 (AMPKα1) from Megalobrama amblycephala and investigate the transcriptional response of this kinase to nutrient restriction and glucose and insulin loadings. The cDNA… read more here.
Keywords: glucose insulin; kinase; nutrient restriction; amp activated ... See more keywords
A 12‐week randomized clinical trial investigating the potential for sucralose to affect glucose homeostasis
Sign Up to like & getrecommendations! Published in 2017 at "Regulatory Toxicology and Pharmacology"
DOI: 10.1016/j.yrtph.2017.05.011
Abstract: ABSTRACT The discovery of gut sweet taste receptors has led to speculations that non‐nutritive sweeteners, including sucralose, may affect glucose control. A double‐blind, parallel, randomized clinical trial, reported here and previously submitted to regulatory agencies,… read more here.
Keywords: clinical trial; week; insulin peptide; glucose insulin ... See more keywords
Postprandial amino acid, glucose and insulin responses among healthy adults after a single intake of Lemna minor in comparison with green peas: a randomised trial
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Nutritional Science"
DOI: 10.1017/jns.2019.26
Abstract: Abstract A high protein content combined with its enormous growth capacity make duckweed an interesting alternative protein source, but information about postprandial responses in humans is lacking. The present study aimed to assess the postprandial… read more here.
Keywords: glucose insulin; green peas; lemna minor; amino acid ... See more keywords
An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis
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DOI: 10.1038/s41467-019-10487-4
Abstract: Despite existing reports on differential DNA methylation in type 2 diabetes (T2D) and obesity, our understanding of its functional relevance remains limited. Here we show the effect of differential methylation in the early phases of… read more here.
Keywords: homeostasis; methylation; cross omics; differential methylation ... See more keywords
Preconception Optimization of Glucose and Insulin Metabolism in Women Wanting to Conceive – High Rate of Spontaneous Conception Prior to Planned Assisted Reproduction
Sign Up to like & getrecommendations! Published in 2017 at "Geburtshilfe und Frauenheilkunde"
DOI: 10.1055/s-0043-122279
Abstract: Background A hyperglycemic metabolic status with insulin resistance can have a negative effect on fertility and pregnancy outcomes. The aim of this retrospective study was to investigate disorders of glucose and insulin metabolism in women… read more here.
Keywords: insulin; conception; rate; insulin metabolism ... See more keywords