Long-Term Glucose Restriction with or without Beta-Hydroxybutyrate Enrichment Distinctively Alters Epithelial-Mesenchymal Transition-Related Signaling in Ovarian Cancer Cells.
Sign Up to like & getrecommendations! Published in 2021 at "Nutrition and cancer"
DOI: 10.1080/01635581.2021.1971268
Abstract: Dear Editor,We read with interest the recent research article entitled “Long-Term Glucose Restriction with or without Beta-Hydroxybutyrate Enrichment Distinctively Alters Epithelial-Mesenchymal Tra... read more here.
Keywords: long term; term glucose; restriction without; glucose restriction ... See more keywords
Life span extension by glucose restriction is abrogated by methionine supplementation: Cross-talk between glucose and methionine and implication of methionine as a key regulator of life span
Sign Up to like & getrecommendations! Published in 2020 at "Science Advances"
DOI: 10.1126/sciadv.aba1306
Abstract: Yeast cells lower their intracellular methionine level in response to glucose restriction to regulate metabolism and life span. Caloric restriction (CR) is known to extend life span across species; however, the molecular mechanisms are not… read more here.
Keywords: methionine; glucose restriction; life span;
Curcumin Treatment in Combination with Glucose Restriction Inhibits Intracellular Alkalinization and Tumor Growth in Hepatoma Cells
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DOI: 10.3390/ijms20102375
Abstract: Dysregulation of cellular energy metabolism is closely linked to cancer development and progression. Calorie or glucose restriction (CR or GR) inhibits energy-dependent pathways, including IGF-1/PI3K/Akt/mTOR, in cancer cells. However, alterations in proton dynamics and reversal… read more here.
Keywords: restriction inhibits; treatment; intracellular alkalinization; glucose restriction ... See more keywords
Glucose restriction drives spatial reorganization of mevalonate metabolism
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DOI: 10.7554/elife.62591
Abstract: Eukaryotes compartmentalize metabolic pathways into sub-cellular domains, but the role of inter-organelle contacts in organizing metabolic reactions remains poorly understood. Here, we show that in response to acute glucose restriction (AGR) yeast undergo metabolic remodeling… read more here.
Keywords: mevalonate metabolism; glucose restriction; mevalonate pathway;