Comparison and screening of bioactive phenolic compounds in different blueberry cultivars: Evaluation of anti-oxidation and α-glucosidase inhibition effect.
Sign Up to like & getrecommendations! Published in 2017 at "Food research international"
DOI: 10.1016/j.foodres.2017.07.004
Abstract: This study was aimed to investigate antioxidation and α-glucosidase inhibition of the bioactive compounds in three cultivars of blueberry ('Northland' (NL) from the hybrid blueberry (V. corymbosum L.×V. angustifolium Aiton), 'Britewell' (BW), and 'Gardenblue' (GB)… read more here.
Keywords: antioxidant activity; blueberry; inhibition; effect ... See more keywords
Synthesis of 7-Azaindole Based Carbohydrazides and 1,3,4-Oxadiazoles; Antioxidant Activity, α-Glucosidase Inhibition Properties and Docking Study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2021.131343
Abstract: ABSTRACT In this current work, 7-azaindole based 1,3,4-oxadiazoles have been successfully prepared by treatment of 3-(hydrazonomethyl)-7-azaindole with the different acyl chlorides or acetic anhydrides to give the corresponding carbohydrazides, followed by iodine mediated synthetic protocol… read more here.
Keywords: antioxidant activity; activity glucosidase; glucosidase inhibition; azaindole based ... See more keywords
Synthesis of Rosmarinic Acid Amides as Antioxidative and Hypoglycemic Agents.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.8b01002
Abstract: Type 2 diabetes mellitus (T2DM) is an important metabolic disorder for which there is an urgent need for new antidiabetic drugs. α-Glucosidase inhibition is an established protocol for T2DM therapy. Because hyperglycemia causes oxidative tissue… read more here.
Keywords: study; rosmarinic acid; glucosidase inhibition; synthesis rosmarinic ... See more keywords
Chemical constituents of Impatiens parvisepala and their α-glucosidase inhibition activity.
Sign Up to like & getrecommendations! Published in 2022 at "Natural product research"
DOI: 10.1080/14786419.2022.2127705
Abstract: The first chemical study of the whole Impatiens parvisepala S. X. Yu & Y. T. Hou led to the isolation of a new triterpene saponin, named Iparvisepala-1 (6) along with ten known compounds, which cover… read more here.
Keywords: glucosidase inhibition; constituents impatiens; impatiens parvisepala; chemical constituents ... See more keywords
Structure-Activity Relationships of N-Cinnamoyl and Hydroxycinnamoyl Amides on α-Glucosidase Inhibition
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Chemistry"
DOI: 10.1155/2017/6080129
Abstract: Currently, there is an increasing interest towards -glucosidase inhibition of various diseases including diabetes mellitus type 2, cancer, HIV, and B- and C-type viral hepatitis. Cinnamic acid derivatives have been shown to be potentially valuable… read more here.
Keywords: cinnamoyl hydroxycinnamoyl; hydroxycinnamoyl amides; inhibition; activity ... See more keywords
Definition of chemical markers for Hancornia speciosa Gomes by chemometric analysis based on the chemical composition of extracts, their vasorelaxant effect and α-glucosidase inhibition.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of ethnopharmacology"
DOI: 10.2139/ssrn.4137027
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Hancornia speciosa Gomes (Apocynaceae) is a tree found in the Brazilian savannah, traditionally used to treat several diseases, including diabetes and hypertension. The anti-hypertensive activity of H. speciosa leaves (HSL) has been demonstrated… read more here.
Keywords: chemical markers; glucosidase inhibition; inhibition; effect ... See more keywords
Fabrication and characterization of glimepiride nanosuspension by ultrasonication-assisted precipitation for improvement of oral bioavailability and in vitro α-glucosidase inhibition
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s210548
Abstract: Purpose We aimed to enhance the solubility, dissolution rate, oral bioavailability, and α-glucosidase inhibition of glimepiride (Glm) by fabricating its nanosuspension using a precipitation–ultrasonication approach. Methods Glm nanosuspensions were fabricated using optimized processing conditions. Characterization… read more here.
Keywords: bioavailability; glucosidase inhibition; microscopy; glm ... See more keywords
Bioassay-guided isolation of Fenghuang Dancong tea constituents with α-glucosidase inhibition activities
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.1050614
Abstract: An α-glucosidase inhibition assay showed the ethanolic extract of Fenghuang Dancong tea had potential α-glucosidase inhibitory activity. The most bioactive fraction, which was obtained via bioassay-guided isolation of the extract, was further purified to create… read more here.
Keywords: guided isolation; glucosidase inhibition; bioassay guided; fenghuang dancong ... See more keywords
Influence of Ultrasound-Assisted Vacuum Drying on Physicochemical Characteristics, Antioxidant Activity, and α-Glucosidase Inhibition Activity of Flos Sophorae Immaturus
Sign Up to like & getrecommendations! Published in 2023 at "Foods"
DOI: 10.3390/foods12030671
Abstract: Flos Sophorae Immaturus (FSI) contains a large number of bioactive substances with antioxidant and hypoglycaemic activity. However, a feasible drying process plays an important role in the retention of its biological activity. The present work… read more here.
Keywords: vacuum; inhibition; flos sophorae; glucosidase inhibition ... See more keywords
Potent in Vitro α-Glucosidase Inhibition of Secondary Metabolites Derived from Dryopteris cycadina
Sign Up to like & getrecommendations! Published in 2019 at "Molecules"
DOI: 10.3390/molecules24030427
Abstract: α-glucosidase is responsible for the hydrolysis of complex carbohydrates into simple absorbable glucose and causes postprandial hyperglycemia. α-glucosidase inhibition is thus the ideal target to prevent postprandial hyperglycemia. The present study was therefore designed to… read more here.
Keywords: dryopteris cycadina; inhibition; glucosidase; secondary metabolites ... See more keywords