Glucosyl Platinum(II) Complexes Inhibit Aggregation of the C-Terminal Region of the Aβ Peptide
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DOI: 10.1021/acs.inorgchem.1c03540
Abstract: Neurodegenerative diseases are often caused by uncontrolled amyloid aggregation. Hence, many drug discovery processes are oriented to evaluate new compounds that are able to modulate self-recognition mechanisms. Herein, two related glycoconjugate pentacoordinate Pt(II) complexes were… read more here.
Keywords: inhibit aggregation; platinum complexes; terminal region; complexes inhibit ... See more keywords