Emergent composite structures following the amorphization of itraconazole with α-glucosyl rutin by over-grinding
Sign Up to like & getrecommendations! Published in 2018 at "Powder Technology"
DOI: 10.1016/j.powtec.2017.10.002
Abstract: Abstract We investigated the use of α-glucosyl rutin (rutin-G) as a grinding aid for wet bead milling. Itraconazole (ITCZ), which has low solubility at physiological pH conditions, was used as a model poorly water-soluble drug.… read more here.
Keywords: rutin grinding; itcz; glucosyl rutin; composite structures ... See more keywords
α-glucosyl-rutin activates immediate early genes in human induced pluripotent stem cells.
Sign Up to like & getrecommendations! Published in 2021 at "Stem cell research"
DOI: 10.1016/j.scr.2021.102511
Abstract: Rutin is a natural flavonoid glycoside found in several vegetables and fruits such as buckwheat and onion. Rutin has a range of pharmacological effects that include anti-oxidant, anti-inflammation, anti-bacterial, and anti-cancer activities. α-glucosyl-rutin (AGR) is… read more here.
Keywords: glucosyl rutin; pluripotent stem; induced pluripotent; stem cells ... See more keywords