Biochemical Characterization and Synthetic Application of α‐1,3‐Glucosyltransferase from Pneumococcus Serotype 18C
Sign Up to like & getrecommendations! Published in 2021 at "ChemCatChem"
DOI: 10.1002/cctc.202100507
Abstract: The enzymatic activity and function of a new α‐1,3‐glucosyltransferase, Cps18CU, derived from Streptococcus pneumoniae serotype 18C was identified for the first time using the enzymatically synthetic disaccharide Rhaβ1,4‐Glcα‐PP‐O(CH2)11‐OPh as the acceptor substrate. Further investigation on… read more here.
Keywords: serotype 18c; biochemical characterization; rha glc; glucosyltransferase ... See more keywords
WP1066, a small molecule inhibitor of the JAK/STAT3 pathway, inhibits ceramide glucosyltransferase activity.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.07.115
Abstract: WP1066 is a well-known inhibitor of the JAK/STAT3 signaling pathway. By a screen of known small molecule inhibitors of various enzymes and protein factors, we identified WP1066 as a ceramide glucosyltransferase inhibitor. Ceramide glucosyltransferase catalyzes… read more here.
Keywords: glucosyltransferase; jak stat3; ceramide glucosyltransferase; inhibitor jak ... See more keywords
A specific UDP-glucosyltransferase catalyzes the formation of triptophenolide glucoside from Tripterygium wilfordii Hook. f.
Sign Up to like & getrecommendations! Published in 2019 at "Phytochemistry"
DOI: 10.1016/j.phytochem.2019.112062
Abstract: Tripterygium wilfordii Hook. f. is a perennial woody vine member of the Celastraceae family. As a traditional Chinese medicine, it contains complex chemical components and exerts various pharmacological activities. In the present study, we identified… read more here.
Keywords: triptophenolide glucoside; tripterygium wilfordii; glucosyltransferase; wilfordii hook ... See more keywords
Molecular cloning and functional characterization of an isoflavone glucosyltransferase from Pueraria thomsonii.
Sign Up to like & getrecommendations! Published in 2022 at "Chinese journal of natural medicines"
DOI: 10.1016/s1875-5364(21)60105-x
Abstract: Pueraria thomsonii has long been used in traditional Chinese medicine. Isoflavonoids are the principle pharmacologically active components, which are primarily observed as glycosyl-conjugates and accumulate in P. thomsonii roots. However, the molecular mechanisms underlying the… read more here.
Keywords: glucosyltransferase; pueraria thomsonii; cloning functional; functional characterization ... See more keywords
Fermentative Production of Phenolic Glucosides by Escherichia coli with an Engineered Glucosyltransferase from Rhodiola sachalinensis.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.7b00981
Abstract: Three rosmarinic acid analogs produced by recombinant Escherichia coli, two xanthones from fungi and honokiol from plants, were explored as the substrates of E. coli harboring a glucosyltransferase mutant UGT73B6FS to generate phenolic glucosides. Six… read more here.
Keywords: glucosides escherichia; production phenolic; escherichia coli; glucosyltransferase ... See more keywords
In Vitro Synthesis of Branchless Linear (1 → 6)-α-d-Glucan by Glucosyltransferase K: Mechanical and Swelling Properties of Its Hydrogels Crosslinked with Diglycidyl Ethers
Sign Up to like & getrecommendations! Published in 2020 at "ACS Omega"
DOI: 10.1021/acsomega.0c04699
Abstract: A hydrogel was prepared from a polysaccharide, enzymatically synthesized through a one-pot reaction in aqueous solution, and its properties as a functional material were evaluated. Enzymatic synthesis using glucosyltransferase K obtained from Streptococcus salivarius ATCC… read more here.
Keywords: diglycidyl ethers; linear glucan; synthesis branchless; glucosyltransferase ... See more keywords
Regulation of the small GTPase Rab1 function by a bacterial glucosyltransferase
Sign Up to like & getrecommendations! Published in 2018 at "Cell Discovery"
DOI: 10.1038/s41421-018-0055-9
Abstract: Posttranslational modification of key host proteins by virulence factors is an important theme in bacterial pathogenesis. A remarkable example is the reversible modifications of the small GTPase Rab1 by multiple effectors of the bacterial pathogen… read more here.
Keywords: glucosyltransferase; rab1; small gtpase; gtpase ... See more keywords
Structural basis of Notch O-glucosylation and O–xylosylation by mammalian protein–O-glucosyltransferase 1 (POGLUT1)
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-00255-7
Abstract: Protein O-glucosyltransferase 1/Rumi-mediated glucosylation of Notch epidermal growth factor-like (EGF-like) domains plays an important role in Notch signaling. Protein O-glucosyltransferase 1 shows specificity for folded EGF-like domains, it can only glycosylate serine residues in the… read more here.
Keywords: egf like; notch; glucosyltransferase; protein glucosyltransferase ... See more keywords
Application of Racemization Process to Dynamic Resolution of (RS)-Phenylephrine to (R)-Phenylephrine β-D-Glucoside by Nicotiana tabacum Glucosyltransferase
Sign Up to like & getrecommendations! Published in 2018 at "Natural Product Communications"
DOI: 10.1177/1934578x1801301113
Abstract: Enzymatic glucosylation of racemic phenylephrine by glucosyltransferase from Nicotiana tabacum gave (R)-phenylephrine glucoside and recovered (S)-phenylephrine. [RuCl2(p-cymene)]2 complex associated with simple hemisalen ligands or zeolite were able to racemize (S)-phenylephrine. The [RuCl2(p-cymene)]2/Ligand/TEMPO or zeolite racemization… read more here.
Keywords: racemization; glucosyltransferase; nicotiana tabacum; phenylephrine ... See more keywords
Auxin-Glucose Conjugation Protects the Rice (Oryza sativa L.) Seedlings Against Hydroxyurea-Induced Phytotoxicity by Activating UDP-Glucosyltransferase Enzyme
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2021.767044
Abstract: Hydroxyurea (HU) is the replication stress known to carry out cell cycle arrest by inhibiting ribonucleotide reductase (RNR) enzyme upon generating excess hydrogen peroxide (H2O2) in plants. Phytohormones undergo synergistic and antagonistic interactions with reactive… read more here.
Keywords: enzyme; conjugation; stress; auxin glucose ... See more keywords
Synthesis of Mono- and Di-Glucosides of Zearalenone and α-/β-Zearalenol by Recombinant Barley Glucosyltransferase HvUGT14077
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DOI: 10.3390/toxins9020058
Abstract: Zearalenone (ZEN) is an estrogenic mycotoxin occurring in Fusarium-infected cereals. Glucosylation is an important plant defense mechanism and generally reduces the acute toxicity of mycotoxins to humans and animals. Toxicological information about ZEN-glucosides is limited… read more here.
Keywords: barley; zen glucoside; hvugt14077; glucosyltransferase ... See more keywords