Development and validation of ultra-high-performance liquid chromatography-MS method for the determination of raloxifene and its phase II metabolites in plasma: Application to pharmacokinetic studies in rats.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of separation science"
DOI: 10.1002/jssc.202000835
Abstract: The aim of this study is to establish a reliable LC-MS method to simultaneously quantitate raloxifene, and its major metabolites, raloxifene-6-glucuronide, raloxifene-4'-glucuronide and raloxifene-6-sulfate in rat plasma samples for pharmacokinetic studies. The separation of the… read more here.
Keywords: pharmacokinetic studies; glucuronide raloxifene; method; raloxifene glucuronide ... See more keywords