Driving to a Better Understanding of Acyl Glucuronide Transformations Using NMR and Molecular Modeling.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.1c00366
Abstract: Acyl glucuronide (AG) metabolites of carboxylic acid-containing drugs and products of their transformations have long been implicated in drug-induced liver injury (DILI). To inform on the DILI risk arising from AG reactive intermediates, a comprehensive… read more here.
Keywords: better understanding; acyl glucuronide; understanding acyl; driving better ... See more keywords