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Published in 2021 at "Cancer cell"
DOI: 10.1016/j.ccell.2020.12.020
Abstract: Targeted protein degradation is an emerging technology for drug development. An article published in Nature reported a novel mechanism of targeted protein degradation triggered by small-molecule-induced polymerization of the oncogenic transcription factor BCL6.
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Keywords:
degradation;
proteins targeted;
targeted degradation;
gluing proteins ... See more keywords