The GluN3-containing NMDA receptors
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DOI: 10.1080/19336950.2025.2490308
Abstract: ABSTRACT N-methyl-D-aspartate receptors (NMDARs) are heterotetrameric ion channels that play crucial roles in brain function. Among all the NMDAR subtypes, GluN1-N3 receptors exhibit unique agonist binding and gating properties. Unlike “conventional” GluN1-N2 receptors, which require… read more here.
Keywords: nmda receptors; glun1 receptors; brain; containing nmda ... See more keywords
Identification of a Subtype-Selective Allosteric Inhibitor of GluN1/GluN3 NMDA Receptors
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DOI: 10.3389/fphar.2022.888308
Abstract: N-methyl-D-aspartate receptors (NMDARs) are Ca2+-permeable ionotropic glutamate receptors (iGluRs) in the central nervous system and play important roles in neuronal development and synaptic plasticity. Conventional NMDARs, which typically comprise GluN1 and GluN2 subunits, have different… read more here.
Keywords: glun3 containing; glun1 glun3; inhibitor glun1; glun1 ... See more keywords