Coumestrol pre‐treatment improves spatial learning and memory deficits following transient cerebral ischemia recruiting hippocampal GluR2 AMPA receptors
Sign Up to like & getrecommendations! Published in 2022 at "Hippocampus"
DOI: 10.1002/hipo.23418
Abstract: Transient global ischemia is a leading cause of learning and memory dysfunction and induces a pattern of delayed neuronal death in the CA1 subfield of the hippocampus by down‐regulating GluR2 mRNA AMPA receptors in this… read more here.
Keywords: ischemia; ampa receptors; memory deficits; memory ... See more keywords
Pumilio2 regulates synaptic plasticity via translational repression of synaptic receptors in mice
Sign Up to like & getrecommendations! Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.24345
Abstract: PUMILIO 2 (PUM2) is a member of Pumilio and FBF (PUF) family, an RNA binding protein family with phylogenetically conserved roles in germ cell development. The Drosophila Pumilio homolog is also required for dendrite morphogenesis… read more here.
Keywords: pum2; repression; temporal lobe; via translational ... See more keywords
Riluzole induces LTD of spinal nociceptive signaling via postsynaptic GluR2 receptors
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pain Research"
DOI: 10.2147/jpr.s169686
Abstract: Purpose Riluzole – a major therapeutic medicine for patients with amyotrophic lateral sclerosis – reportedly has anti-nociceptive and anti-allodynic efficacies in neuropathic pain models. However, little is known about its effect on neurotransmission in the… read more here.
Keywords: spinal nociceptive; nociceptive signaling; riluzole induces; ltd spinal ... See more keywords
Intravenous Injection of GluR2-3Y Inhibits Repeated Morphine-Primed Reinstatement of Drug Seeking in Rats
Sign Up to like & getrecommendations! Published in 2023 at "Brain Sciences"
DOI: 10.3390/brainsci13040590
Abstract: Studies have demonstrated that the α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor is essential to drug addiction. In this study, we explored the influence of GluR2-3Y, an interfering peptide to prevent the endocytosis of AMPA receptors containing the… read more here.
Keywords: repeated morphine; injection glur2; intravenous injection; morphine ... See more keywords
Computational Investigation into the Interactions of Traditional Chinese Medicine Molecules of WenQingYin with GluR2
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms18071443
Abstract: Docking and molecular dynamics simulations have been carried out to investigate the interaction of a traditional Chinese medicine, WenQingYin, with the glutamate receptor 2 (GluR2) subunit of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor. Four representative drug… read more here.
Keywords: medicine; traditional chinese; ligand binding; chinese medicine ... See more keywords