Unraveling GLUT‐mediated transcytosis pathway of glycosylated nanodisks
Sign Up to like & getrecommendations! Published in 2021 at "Asian Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ajps.2020.07.001
Abstract: Glucose transporter (GLUT)-mediated transcytosis has been validated as an efficient method to cross the blood-brain barrier and enhance brain transport of nanomedicines. However, the transcytosis process remains elusive. Glycopeptide-modified nanodisks (Gly-A7R-NDs), which demonstrated high capacity… read more here.
Keywords: gly a7r; glut mediated; glut; mediated transcytosis ... See more keywords
Discrimination of GLUTs by Fructose Isomers Enables Simultaneous Screening of GLUT5 and GLUT2 Activity in Live Cells.
Sign Up to like & getrecommendations! Published in 2023 at "ACS chemical biology"
DOI: 10.1021/acschembio.2c00682
Abstract: Facilitative carbohydrate transporters (GLUTs, SLC2 gene family) are transmembrane proteins transporting hexoses and other sugars based on cellular metabolic demands. While a direct link between GLUTs and metabolic disorders has framed them as important biological… read more here.
Keywords: glut5 glut2; glut2 activity; activity live; glut ... See more keywords
Effects of Stevioside on the Expressions of GLUT 1, GLUT 3, and GLUT 4 Proteins in Diabetic Rat Placenta
Sign Up to like & getrecommendations! Published in 2022 at "Planta Medica"
DOI: 10.1055/a-2003-9463
Abstract: Abstract The placenta provides maternal–fetal nutrient transport. The primary source of energy for fetus development is glucose and maternal–fetal glucose transport occurs through glucose transporters (GLUTs). Stevioside, a component of Stevia rebaudiana Bertoni, is used… read more here.
Keywords: glut glut; glut proteins; effects stevioside; glut ... See more keywords
Diagnostic value of GLUT-1 in distinguishing malignant mesothelioma from reactive mesothelial cells: a meta-analysis
Sign Up to like & getrecommendations! Published in 2020 at "Biomarkers"
DOI: 10.1080/1354750x.2020.1714735
Abstract: Abstract Background: Previous studies have demonstrated the diagnostic value of glucose transporter 1 (GLUT-1) to distinguish malignant mesothelioma (MM) from reactive mesothelial cells (RMC), but the results are inconsistent. The purpose of this meta-analysis is… read more here.
Keywords: diagnostic value; meta analysis; malignant mesothelioma; mesothelioma reactive ... See more keywords
Effect of Glut‐1 and HIF‐1α double knockout by CRISPR/CAS9 on radiosensitivity in laryngeal carcinoma via the PI3K/Akt/mTOR pathway
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17303
Abstract: Hypoxic resistance is the main obstacle to radiotherapy for laryngeal carcinoma. Our previous study indicated that hypoxia‐inducible factor 1α (HIF‐1α) and glucose transporter 1 (Glut‐1) double knockout reduced tumour biological behaviour in laryngeal carcinoma cells.… read more here.
Keywords: akt mtor; pi3k akt; glut; hif ... See more keywords
Nitric Oxide–Mediated Regulation of GLUT by T3 and Follicle-Stimulating Hormone in Rat Granulosa Cells
Sign Up to like & getrecommendations! Published in 2017 at "Endocrinology"
DOI: 10.1210/en.2016-1864
Abstract: Thyroid hormones are important for normal reproductive function. Although 3,5,3'-triiodothyronine (T3) enhances follicle-stimulating hormone (FSH)-induced preantral follicle growth and granulosa cells development in vitro, little is known about the molecular mechanisms regulating ovarian development via… read more here.
Keywords: granulosa cells; glut; glucose uptake; glut expression ... See more keywords
GLUT-1 overexpression as an unfavorable prognostic biomarker in patients with colorectal cancer
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.14352
Abstract: Background Glucose transporter-1 (GLUT-1) exhibits altered expression in colorectal cancer (CRC). The aim of this study was to explore the association between GLUT-1 and survival conditions, as well as clinical features in CRC by meta-analysis.… read more here.
Keywords: biomarker; colorectal cancer; glut; cancer ... See more keywords
In vivo evaluation of the effects of simultaneous inhibition of GLUT-1 and HIF-1α by antisense oligodeoxynucleotides on the radiosensitivity of laryngeal carcinoma using micro 18F-FDG PET/CT
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.16671
Abstract: Purpose Hypoxia-inducible factor 1α (HIF-1α) and glucose transporter-1 (GLUT-1) are two important hypoxic markers associated with the radioresistance of cancers including laryngeal carcinoma. We evaluated whether the simultaneous inhibition of GLUT-1 and HIF-1α expression improved… read more here.
Keywords: hif; laryngeal carcinoma; glut; 18f fdg ... See more keywords
Construction of a GLUT-1 and HIF-1α gene knockout cell model in HEp-2 cells using the CRISPR/Cas9 technique
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Management and Research"
DOI: 10.2147/cmar.s183859
Abstract: Background Glucose transporter (GLUT)-mediated glucose uptake is an important process in the development of laryngeal carcinoma, one of the most common malignancies of the head and neck. GLUT-1, together with HIF-1α, is also an indicator… read more here.
Keywords: hif; gene knockout; hif glut; hep cells ... See more keywords
MicroRNA-140-5p is Downregulated in Osteosarcoma and Overexpression of MicroRNA-140-5p Inhibits Cancer Cell Proliferation by Downregulating GLUT-1
Sign Up to like & getrecommendations! Published in 2021 at "OncoTargets and therapy"
DOI: 10.2147/ott.s289229
Abstract: Background MicroRNA-140-5p plays pivotal role in different types of human malignancies, while its involvement in osteosarcoma is unknown. Objective Our study aimed to investigate the functionality of microRNA-140-5p in osteosarcoma. Methods Plasma levels of microRNA-140-5p… read more here.
Keywords: cell proliferation; cell; microrna 140; glut ... See more keywords
Changes in the Composition of Aroma and Phenolic Compounds Induced by Different Enological Practices of Croatian White Wine
Sign Up to like & getrecommendations! Published in 2019 at "Polish Journal of Food and Nutrition Sciences"
DOI: 10.31883/pjfns/112328
Abstract: The composition of wine and, consequently, its overall quality depends on numerous factors and their interactions. During grape ripening, signifi cant changes occur in the chemical composition of grapes where, primarily, increase of sugar levels… read more here.
Keywords: aroma phenolic; wine; glut; glut 3sh ... See more keywords