Glucose consumption and uptake in HepG2 cells is improved by aqueous extracts from leaves, but not rhizomes, of Posidonia oceanica (L.) Delile via GLUT-4 upregulation
Sign Up to like & getrecommendations! Published in 2025 at "Protoplasma"
DOI: 10.1007/s00709-025-02076-8
Abstract: The endemic Mediterranean seagrass Posidonia oceanica is a valuable source of natural bioactive compounds that possess significant therapeutic potential. Here, we examined whether aqueous extracts of rhizomes (RE) and green leaves (GLE) of P. oceanica… read more here.
Keywords: posidonia oceanica; glut; hepg2; glucose consumption ... See more keywords
Unraveling GLUT‐mediated transcytosis pathway of glycosylated nanodisks
Sign Up to like & getrecommendations! Published in 2021 at "Asian Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ajps.2020.07.001
Abstract: Glucose transporter (GLUT)-mediated transcytosis has been validated as an efficient method to cross the blood-brain barrier and enhance brain transport of nanomedicines. However, the transcytosis process remains elusive. Glycopeptide-modified nanodisks (Gly-A7R-NDs), which demonstrated high capacity… read more here.
Keywords: gly a7r; glut mediated; glut; mediated transcytosis ... See more keywords
Discrimination of GLUTs by Fructose Isomers Enables Simultaneous Screening of GLUT5 and GLUT2 Activity in Live Cells.
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DOI: 10.1021/acschembio.2c00682
Abstract: Facilitative carbohydrate transporters (GLUTs, SLC2 gene family) are transmembrane proteins transporting hexoses and other sugars based on cellular metabolic demands. While a direct link between GLUTs and metabolic disorders has framed them as important biological… read more here.
Keywords: glut5 glut2; glut2 activity; activity live; glut ... See more keywords
Effects of Stevioside on the Expressions of GLUT 1, GLUT 3, and GLUT 4 Proteins in Diabetic Rat Placenta
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DOI: 10.1055/a-2003-9463
Abstract: Abstract The placenta provides maternal–fetal nutrient transport. The primary source of energy for fetus development is glucose and maternal–fetal glucose transport occurs through glucose transporters (GLUTs). Stevioside, a component of Stevia rebaudiana Bertoni, is used… read more here.
Keywords: glut glut; glut proteins; effects stevioside; glut ... See more keywords
Diagnostic value of GLUT-1 in distinguishing malignant mesothelioma from reactive mesothelial cells: a meta-analysis
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DOI: 10.1080/1354750x.2020.1714735
Abstract: Abstract Background: Previous studies have demonstrated the diagnostic value of glucose transporter 1 (GLUT-1) to distinguish malignant mesothelioma (MM) from reactive mesothelial cells (RMC), but the results are inconsistent. The purpose of this meta-analysis is… read more here.
Keywords: diagnostic value; meta analysis; malignant mesothelioma; mesothelioma reactive ... See more keywords
154 GLUT-1 Positivity: The Hidden Pitfall of Misdiagnosing Verrucous Venous Malformation as Infantile Hemangioma
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DOI: 10.1093/ajcp/aqaf121.088
Abstract: Verrucous venous malformation (VVM), or verrucous hemangioma (VH), is a rare congenital vascular anomaly that shows immunoreactivity to GLUT-1, often misdiagnosed as infantile hemangioma (IH). 18-year-old female presented with solitary, intermittently painful, and ulcerated lesion… read more here.
Keywords: glut; verrucous venous; hemangioma; venous malformation ... See more keywords
Effect of Glut‐1 and HIF‐1α double knockout by CRISPR/CAS9 on radiosensitivity in laryngeal carcinoma via the PI3K/Akt/mTOR pathway
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17303
Abstract: Hypoxic resistance is the main obstacle to radiotherapy for laryngeal carcinoma. Our previous study indicated that hypoxia‐inducible factor 1α (HIF‐1α) and glucose transporter 1 (Glut‐1) double knockout reduced tumour biological behaviour in laryngeal carcinoma cells.… read more here.
Keywords: akt mtor; pi3k akt; glut; hif ... See more keywords
Glut-1 exerts anti-tumor activity in glioma by regulating AKT / mTOR signaling pathway
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DOI: 10.1177/09287329241304910
Abstract: Objective Glioma is a common tumor in neurosurgery. Glut-1 is the main carrier of glucose uptake by cells and can provide energy through the glycolytic pathway. However, the role and related mechanisms of Glut-1 in… read more here.
Keywords: mtor signaling; glut; akt mtor; tumor ... See more keywords
Nitric Oxide–Mediated Regulation of GLUT by T3 and Follicle-Stimulating Hormone in Rat Granulosa Cells
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DOI: 10.1210/en.2016-1864
Abstract: Thyroid hormones are important for normal reproductive function. Although 3,5,3'-triiodothyronine (T3) enhances follicle-stimulating hormone (FSH)-induced preantral follicle growth and granulosa cells development in vitro, little is known about the molecular mechanisms regulating ovarian development via… read more here.
Keywords: granulosa cells; glut; glucose uptake; glut expression ... See more keywords
GLUT-1 overexpression as an unfavorable prognostic biomarker in patients with colorectal cancer
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DOI: 10.18632/oncotarget.14352
Abstract: Background Glucose transporter-1 (GLUT-1) exhibits altered expression in colorectal cancer (CRC). The aim of this study was to explore the association between GLUT-1 and survival conditions, as well as clinical features in CRC by meta-analysis.… read more here.
Keywords: biomarker; colorectal cancer; glut; cancer ... See more keywords
In vivo evaluation of the effects of simultaneous inhibition of GLUT-1 and HIF-1α by antisense oligodeoxynucleotides on the radiosensitivity of laryngeal carcinoma using micro 18F-FDG PET/CT
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DOI: 10.18632/oncotarget.16671
Abstract: Purpose Hypoxia-inducible factor 1α (HIF-1α) and glucose transporter-1 (GLUT-1) are two important hypoxic markers associated with the radioresistance of cancers including laryngeal carcinoma. We evaluated whether the simultaneous inhibition of GLUT-1 and HIF-1α expression improved… read more here.
Keywords: hif; laryngeal carcinoma; glut; 18f fdg ... See more keywords