Arsenic impairs GLUT1 trafficking through the inhibition of the calpain system in lymphocytes.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology and applied pharmacology"
DOI: 10.1016/j.taap.2019.114700
Abstract: Exposure to arsenic is associated with increased risk of developing insulin resistance and type 2 diabetes. The proteases calpain-1 (CAPN1), calpain-2 (CAPN2) and calpain-10 (CAPN10) and their endogenous inhibitor calpastatin (CAST) regulate glucose uptake in… read more here.
Keywords: calpain; glut1 trafficking; glucose uptake; impairs glut1 ... See more keywords
Visualization of GLUT1 Trafficking in Live Cancer Cells by the Use of a Dual-Fluorescence Reporter
Sign Up to like & getrecommendations! Published in 2020 at "ACS Omega"
DOI: 10.1021/acsomega.0c01054
Abstract: Glucose metabolism is an essential process for energy production and cell survival for both normal and abnormal cellular metabolism. Several glucose transporter/solute carrier 2A (GLUT/SLC2A) superfamily members, including glucose transporter 1 (GLUT1), have been shown… read more here.
Keywords: fluorescence; egfp glut1; glut1 trafficking; glut1 ... See more keywords