Glucose transporter 2 in common carp (Cyprinus carpio L.): molecular cloning, tissue expression, and the responsiveness to glucose, insulin, and glucagon
Sign Up to like & getrecommendations! Published in 2020 at "Fish Physiology and Biochemistry"
DOI: 10.1007/s10695-020-00782-z
Abstract: Glucose transporter 2 (glut2) has been studied in mammals, aves, and several fish, while the comparative studies of glut2 in common carp are still lacking. In this study, glut2 was firstly isolated and characterized from… read more here.
Keywords: insulin; glucose transporter; common carp; expression ... See more keywords
Specific Lactobacillus probiotic strains decrease transepithelial glucose transport through GLUT2 downregulation in intestinal epithelial cell models.
Sign Up to like & getrecommendations! Published in 2020 at "Nutrition research"
DOI: 10.1016/j.nutres.2020.11.008
Abstract: Although human clinical studies have suggested probiotic effects on blood glucose levels, knowledge about molecular mechanisms is still scarce. To test the hypothesis that selected Lactobacillus probiotic bacteria could regulate the activity of enterocyte glucose… read more here.
Keywords: glucose transport; lactobacillus probiotic; glut2; transepithelial glucose ... See more keywords
Clinical big-data-based design of GLUT2-targeted carbon nanodots for accurate diagnosis of hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2022 at "Nanoscale"
DOI: 10.1039/d2nr04238j
Abstract: Despite advances in diagnostic and therapeutic methods, the prognosis of patients with hepatocellular carcinoma (HCC) remains poor due to the delay in diagnosis. Herein, we aimed to discover a highly sensitive and specific biomarker for… read more here.
Keywords: glut2; hepatocellular carcinoma; big data; hcc ... See more keywords
p38γ MAPK Is Essential for Aerobic Glycolysis and Pancreatic Tumorigenesis
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/0008-5472.can-19-3281
Abstract: These findings show that p38γ links KRAS oncogene signaling and the Warburg effect through PFKBF3 and Glut2 to promote pancreatic tumorigenesis, which can be disrupted via inhibition of p38γ and PFKFB3. KRAS is mutated in… read more here.
Keywords: pfkfb3; tumorigenesis; aerobic glycolysis; p38 ... See more keywords
17β-Estradiol Regulates Glucose Metabolism and Insulin Secretion in Rat Islet β Cells Through GPER and Akt/mTOR/GLUT2 Pathway
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2019.00531
Abstract: Aims: To explore the molecular mechanism by which 17β-estradiol (estrogen 2, E2) regulates glucose transporter 2 (GLUT2) and insulin secretion in islet β cells through G protein-coupled estrogen receptor (GPER) via Akt/mTOR pathway. Methods: SPF-grade… read more here.
Keywords: insulin; insulin secretion; akt mtor; glut2 ... See more keywords
Normal β-Cell Glut2 Expression Is not Required for Regulating Glucose-Stimulated Insulin Secretion and Systemic Glucose Homeostasis in Mice
Sign Up to like & getrecommendations! Published in 2023 at "Biomolecules"
DOI: 10.3390/biom13030540
Abstract: Objective: Glucose transporter 2 (GLUT2) is expressed in the pancreatic β-cell, intestine, liver, and kidney in mice. Although GLUT2 is considered as a major regulator of insulin secretion, in vivo contribution of β-cell Glut2 to… read more here.
Keywords: glut2; cell; glucose; secretion ... See more keywords
Understanding the Role of GLUT2 in Dysglycemia Associated with Fanconi–Bickel Syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10092114
Abstract: Fanconi–Bickel Syndrome (FBS) is a rare disorder of carbohydrate metabolism that is characterized by the accumulation of glycogen mainly in the liver. It is inherited in an autosomal recessive manner due to mutations in the… read more here.
Keywords: glut2; bickel syndrome; expression; dysglycemia ... See more keywords