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Published in 2020 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2020.06.019
Abstract: Phosphoinositides are important signaling molecules involved in the regulation of vesicular trafficking. It has been implicated that phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2] is involved in insulin-regulated GLUT4 translocation in adipocytes. However, it remains unclear where and how…
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Keywords:
insulin;
vesicle;
trafficking;
vesicle docking ... See more keywords
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Published in 2017 at "Journal of Diabetes Research"
DOI: 10.1155/2017/1683678
Abstract: Insulin increases glucose uptake and storage in muscle and adipose cells, which is accomplished through the mobilization of intracellular GLUT4 storage vesicles (GSVs) to the cell surface upon stimulation. Importantly, the dysfunction of insulin-regulated GLUT4…
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Keywords:
spatiotemporal regulators;
insulin;
glut4 vesicle;
vesicle exocytosis ... See more keywords