Glutamate Carrier Involvement in Mitochondrial Dysfunctioning in the Brain White Matter
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DOI: 10.3389/fmolb.2020.00151
Abstract: Glutamate homeostasis is an important determinant of health of the central nervous system (CNS). Mitochondria play crucial roles in glutamate metabolism, especially in processes with a high energy demand such as action potential generation. Mitochondrial… read more here.
Keywords: mitochondrial dysfunctioning; carrier involvement; glutamate carrier; involvement mitochondrial ... See more keywords
Deficiency of Mitochondrial Aspartate-Glutamate Carrier 1 Leads to Oligodendrocyte Precursor Cell Proliferation Defects Both In Vitro and In Vivo
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DOI: 10.3390/ijms20184486
Abstract: Aspartate-Glutamate Carrier 1 (AGC1) deficiency is a rare neurological disease caused by mutations in the solute carrier family 25, member 12 (SLC25A12) gene, encoding for the mitochondrial aspartate-glutamate carrier isoform 1 (AGC1), a component of… read more here.
Keywords: glutamate carrier; proliferation; carrier; aspartate glutamate ... See more keywords
Aspartate-glutamate carrier 2 (citrin): a role in glucose and amino acid metabolism in the liver.
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DOI: 10.5483/bmbrep.2023-0052
Abstract: Aspartate-glutamate carrier 2 (AGC2, citrin) is a mitochondrial carrier expressed in the liver that transports aspartate from mitochondria into cytosol in exchange with glutamate. The AGC2 is the main component of malate-aspartate shuttle (MAS) that… read more here.
Keywords: aspartate glutamate; liver; glutamate; glutamate carrier ... See more keywords