Effects of CMF and MET on glutamate and dopamine levels in the brain, and their impact on cognitive function.
Sign Up to like & getrecommendations! Published in 2022 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202204_28465
Abstract: OBJECTIVE Chemotherapy can cause cognitive impairment in cancer survivors. CMF, the combination of cyclophosphamide (CYP), methotrexate (MTX), and 5-fluorouracil (5-FU), is employed for the treatment of several types of cancers, such as metastatic breast cancer.… read more here.
Keywords: cmf met; glutamate dopamine; brain; dopamine levels ... See more keywords
Initial elevations in glutamate and dopamine neurotransmission decline with age, as does exploratory behavior, in LRRK2 G2019S knock-in mice
Sign Up to like & getrecommendations! Published in 2017 at "eLife"
DOI: 10.7554/elife.28377
Abstract: LRRK2 mutations produce end-stage Parkinson’s disease (PD) with reduced nigrostriatal dopamine, whereas, asymptomatic carriers have increased dopamine turnover and altered brain connectivity. LRRK2 pathophysiology remains unclear, but reduced dopamine and mitochondrial abnormalities occur in aged… read more here.
Keywords: dopamine; gki mice; decline age; mice ... See more keywords
Decreased Serum Glutamate Levels in Male Adults with Internet Gaming Disorder: A Pilot Study
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Psychopharmacology and Neuroscience"
DOI: 10.9758/cpn.2018.16.3.276
Abstract: Objective Alteration in glutamatergic neurotransmission and dopaminergic dysfunction has been implicated in both the initiation and expression of addiction related behaviors. This pilot study was aimed to investigate the serum levels of glutamate and dopamine… read more here.
Keywords: levels glutamate; pilot study; serum levels; adults internet ... See more keywords