Characterization of Schistosoma mansoni Glutamate-Gated Chloride Channels.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0635-3_14
Abstract: Electrophysiology is the standard method for characterizing ion channel function. Two-electrode voltage clamp is a robust and relatively simple version which can be applied to the characterization of glutamate-gated chloride channels from Schistosoma mansoni, a… read more here.
Keywords: gated chloride; glutamate gated; chloride channels; schistosoma mansoni ... See more keywords
Molecular characterization of glutamate-gated chloride channel and its possible roles in development and abamectin susceptibility in the rice stem borer, Chilo suppressalis.
Sign Up to like & getrecommendations! Published in 2019 at "Pesticide biochemistry and physiology"
DOI: 10.1016/j.pestbp.2019.01.007
Abstract: Glutamate-gated chloride channels (GluCls) mediate fast inhibitory neurotransmission in invertebrate nervous systems, and are of considerable interest in insecticide discovery. The full length cDNA encoding CsGluCl was cloned from the rice stem borer Chilo suppressalis… read more here.
Keywords: abamectin; gated chloride; glutamate gated; borer chilo ... See more keywords
Biosynthesis and Structure-Activity Relationship Studies of Okaramines That Target Insect Glutamate-Gated Chloride Channels.
Sign Up to like & getrecommendations! Published in 2018 at "ACS chemical biology"
DOI: 10.1021/acschembio.7b00878
Abstract: Prenylated indole alkaloid okaramines selectively target insect glutamate-gated chloride channels (GluCls). Because of their highly complex structures, including azocine and azetidine rings, total synthesis of okaramine A or B has not been achieved, preventing evaluation… read more here.
Keywords: target insect; glutamate gated; structure activity; insect glutamate ... See more keywords
Nodulisporic acid produces direct activation and positive allosteric modulation of AVR-14B, a glutamate-gated chloride channel from adult Brugia malayi
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2111932119
Abstract: Significance Filarial nematodes affect millions of people globally and constitute a serious public health issue in tropical and subtropical regions. Ivermectin (IVM) is used in combination with other chemotherapeutic agents for treatment and control of… read more here.
Keywords: avr 14b; brugia malayi; glutamate gated; nodulisporic acid ... See more keywords