Glutamatergic pathway in depressive-like behavior associated with pentylenetetrazole rat model of epilepsy with history of prolonged febrile seizures.
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DOI: 10.1016/j.lfs.2020.117692
Abstract: BACKGROUND Depression is the most significant cause of suicide among neuropsychiatric illnesses. Major depression further affects the quality of life in an individual with epilepsy. The treatment of depression in an epileptic patient could be… read more here.
Keywords: glutamatergic pathway; depression; like behavior; depressive like ... See more keywords
Δ8-THC Induces Up-Regulation of Glutamatergic Pathway Genes in Differentiated SH-SY5Y: A Transcriptomic Study
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DOI: 10.3390/ijms24119486
Abstract: Cannabinoids, natural or synthetic, have antidepressant, anxiolytic, anticonvulsant, and anti-psychotic properties. Cannabidiol (CBD) and delta-9-tetrahydrocannabinol (Δ9-THC) are the most studied cannabinoids, but recently, attention has turned towards minor cannabinoids. Delta-8-tetrahydrocannabinol (Δ8-THC), an isomer of Δ9-THC,… read more here.
Keywords: glutamatergic pathway; differentiated sy5y; induces regulation; thc induces ... See more keywords