Genetic Deletion of GABAA Receptors Reveals Distinct Requirements of Neurotransmitter Receptors for GABAergic and Glutamatergic Synapse Development
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2019.00217
Abstract: In the adult brain GABAA receptors (GABAARs) mediate the majority of synaptic inhibition that provides inhibitory balance to excitatory drive and controls neuronal output. In the immature brain GABAAR signaling is critical for neuronal development.… read more here.
Keywords: gabaergic glutamatergic; glutamatergic synapses; gabaa receptors; synapse development ... See more keywords
SNAP25 differentially contributes to Gi/o-coupled receptor function at glutamatergic synapses in the nucleus accumbens
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2023.1165261
Abstract: The nucleus accumbens (NAc) guides reward-related motivated behavior implicated in pathological behavioral states, including addiction and depression. These behaviors depend on the precise neuromodulatory actions of Gi/o-coupled G-protein-coupled receptors (GPCRs) at glutamatergic synapses onto medium… read more here.
Keywords: glutamatergic synapses; differentially contributes; contributes coupled; snap25 differentially ... See more keywords
The AMPA receptor-associated protein Shisa7 regulates hippocampal synaptic function and contextual memory
Sign Up to like & getrecommendations! Published in 2017 at "eLife"
DOI: 10.7554/elife.24192
Abstract: Glutamatergic synapses rely on AMPA receptors (AMPARs) for fast synaptic transmission and plasticity. AMPAR auxiliary proteins regulate receptor trafficking, and modulate receptor mobility and its biophysical properties. The AMPAR auxiliary protein Shisa7 (CKAMP59) has been… read more here.
Keywords: receptor; glutamatergic synapses; protein shisa7; memory ... See more keywords